Rapid identification of a catheter-related bloodstream infection using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry Open Access

Abstract

Introduction:

is a large, fusiform, non-sporulating, motile, Gram-negative rod, and is a member of the family in the phylum . Although bacteraemia is extremely rare, severe infections have been reported in immunocompromised patients.

Case presentation:

We present a case of a 69-year-old woman diagnosed with diffuse large B-cell lymphoma, who suffered a catheter-related bloodstream infection due to during the post-autologous peripheral blood progenitor-cell transplantation aplasia phase. In this case, rapid identification of the opportunistic pathogen was achieved using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry directly from a blood culture, with correct identification of the micro-organism within 2 h after the blood culture became positive.

Conclusion:

Rapid identification of this opportunistic pathogen allowed initiation of appropriate antimicrobial therapy, which contributed to a successful clinical outcome for the patient.

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2015-08-01
2024-03-28
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