%0 Journal Article %A Putman, Michael S. %A Shah, Nirav S. %A Husain, Aliya N. %A David, Michael Z. %T Extrapulmonary intrathoracic blastomycosis: a case report and systematic literature review %D 2015 %J JMM Case Reports, %V 2 %N 1 %@ 2053-3721 %C e000022 %R https://doi.org/10.1099/jmmcr.0.000022 %K Blastomyces %K blastomycosis %K mediastinal mass lesion %K Gilchrist's disease %I Microbiology Society, %X Introduction: Mediastinal blastomycosis has been described in multiple case reports, but no review to date has catalogued its various manifestations or response to treatment. Case presentation: An otherwise healthy 18‐year‐old female presented with lymphadenopathy and was found to have a large mediastinal mass concerning for lymphoma. A subsequent biopsy revealed Blastomyces dermatitidis; the patient responded well to therapy with amphotericin B and itraconazole. Similar cases are reviewed and analysed. Conclusion: Mediastinal blastomycosis is a rare but life‐threatening disease manifestation that responds readily to appropriate antifungal therapy. %U https://www.microbiologyresearch.org/content/journal/jmmcr/10.1099/jmmcr.0.000022