1887

Abstract

The prevalence of tetracycline resistance, tetracycline MICs and (O) gene localization were investigated in 83 isolates from patients suffering from acute gastroenteritis in Germany. Combined biochemical and molecular markers identified 74 isolates (89 %) as , including seven atypical isolates that failed to hydrolyse hippurate, and nine isolates (11 %) as . Tetracycline resistance was detected in six out of nine isolates (67 %) and 13 out of 74 isolates (18 %). Low-level tetracycline resistance was observed for (MIC 16 μg ml for all strains), whereas showed high-level resistance (MIC >256 μg ml for all strains). Both low- and high-level tetracycline resistance was associated with the presence of the (O) gene. In , (O) was plasmid-encoded in 54 % of tetracycline-resistant isolates, whereas in , (O) appeared to be located on the chromosome.

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2007-06-01
2019-10-22
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