1887

Abstract

Meticillin-resistant isolates were classified into three mupirocin susceptibility groups by the disc diffusion method using 5 and 200 μg mupirocin discs. The zone diameter observed for a 5 μg disc distinguished Mup from the resistant strains (either Mup or Mup). On the other hand, a 200 μg disc distinguished the high-resistance Mup strains from the other two (Mup or Mup). Thus, the concomitant use of 5 and 200 μg mupirocin discs allowed the clear distinction among the three mupirocin susceptibility groups, Mup, Mup or Mup.

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2007-07-01
2019-11-14
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References

  1. Bastos, M. C. F., Mondino, P. J. J., Azevedo, M. L., Santos, K. R. N. & Giambiagi-deMarval, M. ( 1999; ). Molecular characterization and transfer among Staphylococcus strains of a plasmid conferring high-level resistance to mupirocin. Eur J Clin Microbiol Infect Dis 18, 393–398.[CrossRef]
    [Google Scholar]
  2. CLSI ( 2006; ). Performance Standards for Antimicrobial Disk Susceptibility Tests, 9th edn., approved standard M2-A9. Wayne, PA: Clinical Laboratory Standard Institute.
  3. Deshpande, L. M., Fix, A. M., Pfaller, M. A. & Jones, R. N., SENTRY Antimicrobial Surveillance Program Participants Group ( 2002; ). Emerging elevated mupirocin resistance rates among staphylococcal isolates in the SENTRY Antimicrobial Surveillance Program (2000): correlations of results from disk diffusion, E-test and reference dilution methods. Diagn Microbiol Infect Dis 42, 283–290.[CrossRef]
    [Google Scholar]
  4. Eltringham, I. ( 1997; ). Mupirocin resistance and methicillin-resistant Staphylococcus aureus (MRSA). J Hosp Infect 35, 1–8.
    [Google Scholar]
  5. Finlay, J. E., Millar, L. A. & Poupard, J. A. ( 1997; ). Interpretive criteria for testing susceptibility of staphylococci to mupirocin. Antimicrob Agents Chemother 41, 1137–1139.
    [Google Scholar]
  6. Fuchs, P. C., Jones, R. N. & Barry, A. L. ( 1990; ). Interpretive criteria for disk diffusion susceptibility testing of mupirocin, a topical antibiotic. J Clin Microbiol 28, 608–609.
    [Google Scholar]
  7. Hudson, I. R. ( 1994; ). The efficacy of intranasal mupirocin in the prevention of staphylococcal infections: a review of recent experience. J Hosp Infect 27, 81–98.[CrossRef]
    [Google Scholar]
  8. Lowy, F. D. ( 2003; ). Antimicrobial resistance: the example of Staphylococcus aureus. J Clin Invest 111, 1265–1273.[CrossRef]
    [Google Scholar]
  9. Mondino, P. J. J., Santos, K. R. N., Bastos, M. C. F. & Giambiagi-deMarval, M. ( 2003; ). Improvement of mupirocin E-test for susceptibility testing of Staphylococcus aureus. J Med Microbiol 52, 385–387.[CrossRef]
    [Google Scholar]
  10. Nunes, E. L., Santos, K. R. N., Mondino, P. J., Bastos, M. C. & Giambiagi-deMarval, M. ( 1999; ). Detection of ileS-2 gene encoding mupirocin resistance in methicillin-resistant Staphylococcus aureus by multiplex PCR. Diagn Microbiol Infect Dis 34, 77–81.[CrossRef]
    [Google Scholar]
  11. Palepou, M. F., Johnson, A. P., Cookson, B. D., Beattie, H., Charlett, A. & Woodford, N. ( 1998; ). Evaluation of disc diffusion and Etest for determining the susceptibility of Staphylococcus aureus to mupirocin. J Antimicrob Chemother 42, 577–583.[CrossRef]
    [Google Scholar]
  12. Santos, K. R. N., Teixeira, L. M., Leal, G. S., Fonseca, L. S. & Gontijo Filho, P. P. ( 1999; ). DNA typing of methicillin-resistant Staphylococcus aureus: isolates and factors associated with nosocomial acquisition in two Brazilian university hospitals. J Med Microbiol 48, 17–23.[CrossRef]
    [Google Scholar]
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