1887

Abstract

Two serovar Typhimurium isolates and one serovar Enteritidis isolate that were resistant to 4 μg cefotaxime ml and produced CTX-M-type extended-spectrum -lactamases (ESBLs) were characterized from patients in Hong Kong during 2003–2004. The . Typhimurium strain isolated in 2003 produced a CTX-M-9 ESBL and harboured a gene that was associated with a class I integron-containing gene cassette and similar to those of In60. The second . Typhimurium strain and the . Enteritidis strain, both isolated in 2004, produced CTX-M-14; the former also produced TEM-1. The gene in these two isolates was associated with the insertion sequence IS. The CTX-M genes were present on a transferable plasmid of 62, 70 or 92 kb. PFGE of I-restricted total DNA from the two . Typhimurium isolates indicated that they were not clonally related. These three isolates were also resistant to one of the other non--lactam antimicrobial agents tested. This is the first report of a CTX-M-9 ESBL in in Hong Kong and the presence of and in . Typhimurium.

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2006-09-01
2020-01-23
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