1887

Abstract

The genotypic characteristics and drug susceptibility profiles of clinical isolates of recovered from prison hospital patients in the Tula region (central Russia) during 2001 and 2002 are reported. The emergence of multi-drug-resistant tuberculosis (TB) poses a major health risk to the population, with economic implications for TB control. Prisons serve as a continuous source of TB transmission. The results showed that members of the LAM and Beijing families are major contributors to the epidemiological picture of TB in the population studied. The two families of strains accounted for most of the drug-resistant TB in the population. The genotypic characteristics of the predominant LAM strain that was responsible for 31 % of TB cases in this setting are presented.

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2006-10-01
2019-10-18
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Identification of principal genetic groups using ASD-PCR. [PDF](51 KB)

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Sequences of primers used, drug resistance profile and genotypic characteristics of the isolates and prevalence of drug resistance according to spoligofamily and case category. [PDF](50 KB)

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