Increased recovery of and in association with group A -haemolytic streptococci in healthy children and those with pharyngo-tonsillitis Free

Abstract

The inflamed tonsils harbour numerous types of bacteria, alone or in combination with group A -haemolytic streptococci (GABHS). The cohabitation of the tonsils by GABHS and certain other bacterial species may contribute to the inflammatory process and the failure of penicillin therapy. This study evaluated the recovery of , , and in association with GABHS in healthy children and those with acute pharyngo-tonsillitis (APT). Pharyngo-tonsillar cultures were obtained from 548 children with APT and 866 healthy children. GABHS was recovered from 112 (20.4 %) children with APT. Of the 114 isolates, 32 were recovered in association with GABHS (29 % of all patients who had GABHS) and 82 were isolated without GABHS (19 %) (=0.0267). Of the 69 isolates, 25 were recovered in association with GABHS (22 % of all patients who had GABHS) and 44 were isolated without GABHS (10 %) (=0.0012). In contrast, there was no association between the isolation of GABHS and the recovery of or . . GABHS was recovered from 104 (12 %) healthy children. Of the 69 isolates, 24 were recovered in association with GABHS (23 % of all patients who had GABHS) and 80 were isolated without GABHS (10 %) (=0.006). There was no association between the isolation of GABHS and the recovery of , or . . This study demonstrates an association between the recovery of GABHS and and from pharyngo-tonsillar cultures of patients with APT and from pharyngo-tonsillar cultures of healthy children.

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2006-08-01
2024-03-28
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