Association between cell-bound haemolysin and cell-detaching activity of isolated from children Free

Abstract

Haemolysin (HlyA) produced by cell-detaching , a putative new class of enteric pathogen, is considered to be the main factor responsible for detachment of cells cultured . HlyA is one of the few proteins actively secreted into the medium during exponential growth. In the present study 27 HlyA-positive isolates, randomly selected from stool specimens, produced a cell-bound haemolysin that was detectable during the exponential and stationary growth phases. The influence of both cell-free and cell-bound haemolysins of the selected isolates on cell-detaching activity of was determined. The results suggest that cell-bound haemolysin rather than cell-free HlyA was responsible for the cell-detaching activity of strains tested.

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2006-03-01
2024-03-29
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