1887

Abstract

Infant botulism was confirmed in a 5-month-old female by both isolation of type B and by detection of type B botulinum neurotoxin in rectal washout and faeces. DNA fingerprinting of nine isolates from faeces yielded two different amplified-fragment length polymorphism (AFLP) patterns. was isolated from two of 14 food and drink items from the patient's home: type A was recovered from an opened container of dried rice pudding and type B from opened infant formula milk powder. Ten type B isolates from the opened infant formula yielded four AFLP patterns, two of which were indistinguishable from the clinical isolates. Fifteen unopened foods were tested and type B of a unique AFLP pattern was recovered from one unopened infant formula of the same batch as the opened container. It is suggested that multiple were present in both food and the intestine during infant botulism.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/jmm.0.46000-0
2005-08-01
2019-11-19
Loading full text...

Full text loading...

/deliver/fulltext/jmm/54/8/JM540811.html?itemId=/content/journal/jmm/10.1099/jmm.0.46000-0&mimeType=html&fmt=ahah

References

  1. Armada, M., Love, S., Barrett, E., Monroe, J., Peery, D. & Sobel, J. ( 2003;). Foodborne botulism in a six-month-old infant caused by home-canned baby food. Ann Emerg Med 42, 226–229.[CrossRef]
    [Google Scholar]
  2. Arnon, S. S. ( 1992;). Infant botulism. In Textbook of Pediatric Infectious Diseases, pp. 1095–1102. Edited by R. D. Feigin & J. D. Cherry. Philadelphia: W. B. Saunders.
  3. Arnon, S. S., Midura, T. F., Damus, K., Thompson, B., Wood, R. M. & Chin, J. ( 1979;). Honey and other environmental risk factors for infant botulism. J Pediat 94, 331–336.[CrossRef]
    [Google Scholar]
  4. Aureli, P., Fenicia, L., Pasolini, B., Gianfranceschi, M., McCroskey, L. M. & Hatheway, C. L. ( 1986;). Two cases of type E infant botulism caused by neurotoxigenic Clostridium butyricum in Italy. J Infect Dis 154, 207–211.[CrossRef]
    [Google Scholar]
  5. CDC ( 1997;). Case definitions for infectious conditions under public health surveillance. MMWR Recomm Rep 46(RR-10), 1–55.
    [Google Scholar]
  6. CDC ( 1998;). Botulism in the United States, 1899–1996. Handbook for Epidemiologists, Clinicians and Laboratory Workers. Atlanta: Centers for Disease Control and Prevention.
  7. CDSC ( 1993;). A case of infant botulism. Comm Dis Rep Wkly 3, 129. http://www.hpa.org.uk/cdr/archives/CDR93/cdr2993.pdf
  8. CDSC ( 1994;). A case of infant botulism. Comm Dis Rep Wkly 4, 53. http://www.hpa.org.uk/cdr/archives/cdr94/cdr1294.pdf
  9. Chin, J., Arnon, S. S. & Midura, T. F. ( 1979;). Food and environmental aspects of infant botulism in California. Rev Infect Dis 1, 693–696.[CrossRef]
    [Google Scholar]
  10. Collins, M. D. & East, A. K. ( 1998;). Phylogeny and taxonomy of the food-borne pathogen Clostridium botulinum and its neurotoxins. J Appl Microbiol 84, 5–17.[CrossRef]
    [Google Scholar]
  11. Collins-Thompson, D. L. & Wood, D. S. ( 1993;). Control in dairy products. In Clostridium Botulinum, pp. 261–277. Edited by A. H. W. Hauschild & K. L. Dodds. New York: Marcel Dekker.
  12. Dezfulian, M., McCroskey, L. M., Hatheway, C. L. & Dowell, V. R. ( 1981;). Selective medium for isolation of Clostridium botulinum from human feces. J Clin Microbiol 13, 526–531.
    [Google Scholar]
  13. Franciosa, G., Poushaban, M., Gianfranceschi, M., Gattuso, A., Felicia, L., Ferrini, A. M., Mannoni, V., De Luca, G. & Aureli, P. ( 1999;). Clostridium botulinum spores and toxin in mascarpone cheese and other milk products. J Food Protect 62, 867–871.
    [Google Scholar]
  14. Francis, B., Green, M. & Payne, C. ( 1994;). Applications of GLIM - dilution assay. In The Glim System Release 4, chapter 12, pp. 572–583. Oxford: Oxford University Press.
  15. Gibson, J. R., Slater, E., Tompkins, D. S. & Owen, R. J. ( 1998;). Use of amplified-fragment length polymorphism technique to fingerprint and differentiate isolates of Helicobacter pylori. J Clin Microbiol 36, 2580–2585.
    [Google Scholar]
  16. Guilfoyle, D. E. & Yager, J. F. ( 1983;). Survey of infant foods for Clostridium botulinum spores.J Assoc Off Anal Chem 66, 1302–1304.
    [Google Scholar]
  17. Hatheway, C. L. & McCroskey, L. M. ( 1987;). Examination of feces and serum for diagnosis of infant botulism in 336 patients. J Clin Microbiol 25, 2334–2338.
    [Google Scholar]
  18. Hauschild, A. H. W., Hilsheimer, R., Weiss, K. F. & Burke, R. B. ( 1988;). Clostridium botulinum in honey, syrups and dry infant cereals. J Food Protect 51, 892–894.
    [Google Scholar]
  19. Hielm, S., Björkroth, J., Hyytiä, E. & Korkeala, H. ( 1998;). Prevalence of Clostridium botulinum in Finnish trout farms: pulsed-field gel electrophoresis typing reveals extensive genetic diversity among type E isolates. Appl Environ Microbiol 64, 4161–4167.
    [Google Scholar]
  20. Hyytiä, E., Hielm, S., Björkroth, J. & Korkeala, H. ( 1999;). Biodiversity of Clostridium botulinum type E strains isolated from fish and fishery products. Appl Environ Microbiol 65, 2057–2064.
    [Google Scholar]
  21. Istre, G. R., Compton, R., Novotny, T., Young, J. E., Hatheway, C. L. & Hopkins, R. S. ( 1986;). Infant botulism: three cases in a small town. Am J Dis Child 140, 1013–1014.[CrossRef]
    [Google Scholar]
  22. Jones, S., Huma, Z., Haugh, C., Young, Y., Starer, F. & Sinclair, L. ( 1990;). Central nervous system involvement in infantile botulism. Lancet 335, 228. 228.
    [Google Scholar]
  23. Kautter, D. A., Lilly, T., Solomon, H. M., Lynt, R. K. & Solomon, H. M. ( 1982;). Clostridium botulinum spores in infant foods: a survey. J Food Protect 45, 1028–1029.
    [Google Scholar]
  24. Lilly, T., Rhodehamel, E. J., Kautter, D. A. & Solomon, H. M. ( 1991;). Clostridium botulinum spores in corn syrup and other syrups. J Food Protect 54, 585–587.
    [Google Scholar]
  25. McCroskey, L. M., Hatheway, C. L., Woodruff, B. A., Greenberg, J. A. & Jurgenson, P. ( 1991;). Type F botulism due to neurotoxigenic Clostridium baratii from an unknown source in an adult. J Clin Microbiol 29, 2618–2620.
    [Google Scholar]
  26. McLauchlin, J., Pedraza-Díaz, S., Amar-Hoetzeneder, C. & Nichols, G. L. ( 1999;). Genetic characterisation of Cryptosporidium strains from 218 patients with diarrhoea diagnosed as having sporadic cryptosporidiosis. J Clin Microbiol 37, 3153–3158.
    [Google Scholar]
  27. McLauchlin, J., Salmon, J. E., Ahmed, S., Brazier, J. S., Brett, M. M., George, R. C. & Hood, J. ( 2002;). Amplified fragment length polymorphism (AFLP) analysis of Clostridium novyi, C.perfringens and Bacillus cereus isolated from injecting drug users during 2000. J Med Microbiol 51, 990–1000.
    [Google Scholar]
  28. Midura, T. F. ( 1996;). Update: infant botulism. Clin Microbiol Rev 9, 119–125.
    [Google Scholar]
  29. Nevas, M., Hielm, S., Lindstrom, M., Horn, H., Koivulehto, K. & Korkeala, H. ( 2002;). High prevalence of Clostridium botulinum types A and B in honey samples detected by polymerase chain reaction. Int J Food Microbiol 72, 45–52.[CrossRef]
    [Google Scholar]
  30. Smith, G. E., Hinde, F., Westmoreland, D., Berry, P. R. & Gilbert, R. J. ( 1989;). Infantile botulism. Arch Dis Child 64, 871–872.[CrossRef]
    [Google Scholar]
  31. Turner, H. D., Brett, E. M., Gilbert, R. J., Ghosh, A. C. & Liebeschuetz, H. J. ( 1978;). Infant botulism in England. Lancet i, 1277–1278.
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/jmm.0.46000-0
Loading
/content/journal/jmm/10.1099/jmm.0.46000-0
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error