1887

Abstract

A novel compound 2-(3,4-dimethyl-2,5-dihydro-1H-pyrrol-2-yl)-1-methylethyl pentanoate was isolated from the plant L. The activity of this dihydropyrrole derivative against and species was evaluated by using standard methods approved by the National Committee for Clinical Laboratory Standards. The compound was found to be active against all the species tested, namely , , , and . The MIC at which more than 90 % of growth was inhibited (MIC) by the compound ranged from 21.87 to 43.75 μg ml against various fungal species by microbroth dilution assay. Since the compound 2-(3,4-dimethyl-2,5-dihydro-1H-pyrrol-2-yl)-1-methylethyl pentanoate has antifungal activity it can be explored further to develop new antimycotic drugs.

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2005-06-01
2024-04-24
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