1887

Abstract

In this study the aetiology of community-acquired pneumonia (CAP) in Japan was investigated and the incidence of causative pathogens in ambulatory and hospitalized patients was compared. In addition, the roles of and as causes of CAP were investigated. Five hundred and six patients with CAP who visited an outpatient clinic or were admitted to one of three different hospitals were enrolled in this study; 106 of them were outpatients and 400 were hospitalized patients. Among the 506 CAP cases, was the most common pathogen found in the outpatients and was the most common in the hospitalized patients. No cases of pneumonia were observed and only one patient had an antibody titre suggestive of recent infection with the feline strain of . The incidence of infection with and was higher among the outpatients than among hospitalized patients, whereas the incidence of infection with and was higher among the hospitalized patients. Recognition of these results will allow prompt and appropriate antimicrobial therapy to be provided using Japanese CAP guidelines.

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2005-04-01
2019-08-17
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References

  1. Almirall, J., Morato, I., Riera, F. & 8 other authors ( 1993;). Incidence of community-acquired pneumonia and Chlamydia pneumoniae infection: a prospective multicentre study. Eur Respir J 6, 14–18.
    [Google Scholar]
  2. American Thoracic Society ( 2001;). Guielines for the management of adults with community-acquired pneumonia.Diagnosis, assessment of severity, antimicrobial therapy, and prevention. Am J Respir Crit Care Med 163, 1730–1754.[CrossRef]
    [Google Scholar]
  3. Berntsson, E., Lagergard, T., Strannegard, O. & Trollfors, B. ( 1986;). Etiology of community-acquired pneumonia in out-patients. Eur J Clin Microbiol 5, 446–447.[CrossRef]
    [Google Scholar]
  4. Blanquer, J., Blanquer, R., Borras, R. & 7 other authors ( 1991;). Aetiology of community acquired pneumonia in Valencia, Spain: a multicentre prospective study. Thorax 46, 508–511.[CrossRef]
    [Google Scholar]
  5. Bochud, P.-Y., Moser, F., Erard, P. & 16 other authors ( 2001;). Community-acquired pneumonia.A prospective outpatient study. Medicine 80, 75–87.[CrossRef]
    [Google Scholar]
  6. British Thoracic Society ( 2001;). Guidelines for the management of community-acquired pneumonia in adults. Thorax 56 (Suppl 4), 1–64.
    [Google Scholar]
  7. Cotton, M. M. & Partridge, M. R. ( 1998;). Infection with feline Chlamydia psittaci. Thorax 53, 75–76.
    [Google Scholar]
  8. Everett, K. D. E., Bush, R. M. & Andersen, A. A. ( 1999;). Emended description of the order Chlamydiales, proposal of Parachlamydiaceae fam.nov. and Simkaniaceae fam. nov., each containing one monotypic genus, revised taxonomy of the family Chlamydiaceae, including a new genus and five new species, and standards for the identification of organisms. Int J Syst Bacteriol 49, 415–440.[CrossRef]
    [Google Scholar]
  9. Felmingham, D., Reinert, R. R., Hirakata, Y. & Rodloff, A. ( 2002;). Increasing prevalence of antimicrobial resistance among isolates of Streptococcus pneumoniae from the PROTEKT surveillance study, and comparative in vitro activity of the ketolide, telithromycin. J Antimicrob Chemother 50 (Suppl S1), 25–37.
    [Google Scholar]
  10. Fukushi, H. & Hirai, K. ( 1988;). Immunochemical diversity of the major outer membrane protein of avian and mammalian Chlamydia psittaci. J Clin Microbiol 26, 675–680.
    [Google Scholar]
  11. Griffiths, P. D., Lechler, R. I. & Treharne, J. D. ( 1978;). Unusual chlamydial infection in a human renal allograft recipient. Br Med J 277, 1264–1265.
    [Google Scholar]
  12. Japanese Respiratory Society, Community-acquired Pneumonia Treatment Guideline Creation Committee ( 2000). Practice guidelines for the management of community-acquired pneumonia in adults. Edited by T. Matsushima and others. Tokyo: Japanese Respiratory Society (in Japanese).
  13. Johnson, F. W. A. ( 1992;). Chlamydiosis. Br Vet J 139, 93–101.
    [Google Scholar]
  14. Macfarlane, J. T., Colville, A., Guion, A., Macfarlane, R. M. & Rose, D. H. ( 1993;). Prospective study of aetiology and outcome of adult lower-respiratory-tract infections in the community. Lancet 341, 511–514.[CrossRef]
    [Google Scholar]
  15. Mandell, L. A., Bartlett, J. G., Dowell, S. F., File, T. M., Jr, Musher, D. M. & Whitney, C. ( 2003;). Update of practice guidelines for the management of community-acquired pneumonia in immunocompetent adults. Clin Infect Dis 37, 1405–1433.[CrossRef]
    [Google Scholar]
  16. Marrie, T. J., Peeling, R. W., Fine, M. J., Singer, D. E., Coley, C. M. & Kapoor, W. N. ( 1996;). Ambulatory patients with community-acquired pneumonia: The frequency of atypical agents and clinical course. Am J Med 101, 508–515.[CrossRef]
    [Google Scholar]
  17. Marrie, T. J., Peeling, R. W., Reid, T., De Carolis, E. & Canadian Community-Acquired Pneumonia Investigators ( 2003;). Chlamydia species as a cause of community-acquired pneumonia in Canada. Eur Respir J 21, 779–784.[CrossRef]
    [Google Scholar]
  18. Matsushima, T., Miyashita, N. & File, T. M., Jr ( 2002;). Etiology and management of community-acquired pneumonia in Asia. Curr Opin Infect Dis 15, 157–162.[CrossRef]
    [Google Scholar]
  19. Michetti, G., Pugliese, C., Bamberga, M. & 9 other authors ( 1995;). Community-acquired pneumonia: is there difference in etiology between hospitalized and out-patients? Minerva Med 86, 341–351.
    [Google Scholar]
  20. Miyashita, N. & Matsumoto, A. ( 1992;). Establishment of a particle-counting method for purified elementary bodies of Chlamydiae and evaluation of sensitivities of the IDEIA Chlamydia kit and DNA probe by using the purified elementary bodies. J Clin Microbiol 30, 2911–2916.
    [Google Scholar]
  21. Miyashita, N., Fukano, H., Okimoto, N., Hara, H., Yoshida, K., Niki, Y. & Matsushima, T. ( 2002a;). Clinical presentation of community-acquired Chlamydia pneumoniae pneumonia in adults. Chest 121, 1776–1781.[CrossRef]
    [Google Scholar]
  22. Miyashita, N., Saito, A., Kohno, S. & 7 other authors ( 2002b;). Community-acquired Chlamydia pneumoniae pneumonia in Japan: a prospective multicenter community-acquired pneumonia study. Intern Med 41, 943–949.[CrossRef]
    [Google Scholar]
  23. Miyashita, N., Fukano, H., Yoshida, K., Niki, Y. & Matsushima, T. ( 2003;). Chlamydia pneumoniae infection in adult patients with persistent cough. J Med Microbiol 52, 265–269.[CrossRef]
    [Google Scholar]
  24. Miyashita, N., Fukano, H., Yoshida, K., Niki, Y. & Matsushima, T. ( 2004;). Is it possible to distinguish between atypical pneumonia and bacterial pneumonia?: evaluation of the guidelines for community-acquired pneumonia in Japan. Respir Med 98, 952–960.[CrossRef]
    [Google Scholar]
  25. Regan, R. J., Dathan, J. R. E. & Treharne, J. D. ( 1979;). Infective endocarditis with glomerulonephritis associated with cat chlamydia (C.psittaci) infection. Br Heart J 42, 349–352.[CrossRef]
    [Google Scholar]
  26. Shemer-Avni, Y. & Liberman, D. ( 1995;). Chlamydia pneumoniae-induced ciliostasis in ciliated bronchial epithelial cells. J Infect Dis 171, 1274–1278.[CrossRef]
    [Google Scholar]
  27. Wattanathum, A., Chaoprasong, C., Nunthapisud, P., Chantaratchada, S., Limpairojn, N., Jatakanon, A. & Chanthadisai, N. ( 2003;). Community-acquired pneumonia in southeast Asia: the microbial differences between ambulatory and hospitalized patients. Chest 123, 1512–1519.[CrossRef]
    [Google Scholar]
  28. Yan, C., Fukushi, H., Matsudate, H., Ishihara, K., Yasuda, K., Kitagawa, H., Yamaguchi, T. & Hirai, K. ( 2000;). Seroepidemiological investigation of feline Chlamydiosis in cats and humans in Japan. Microbiol Immunol 44, 155–160.[CrossRef]
    [Google Scholar]
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