1887

Abstract

Detection of the conserved capsule gene is used to distinguish capsulate from non-capsulate . While developing a real-time PCR assay to detect , it was found that probes produced a detectable signal for types a to d, but failed to do so for types e and f. Sequencing revealed differences compared with types a to d within probe binding sites. To prevent misclassification of strains as non-capsulate, assays must detect all capsular types.

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2005-05-01
2020-10-27
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