1887

Abstract

The microbiology of acute and chronic sinusitis has been studied extensively. Establishing the concomitant distribution of the causative organisms in cases that involve multiple sinuses is of scientific and practical importance. This study evaluated the aerobic and anaerobic microbiology of acute and chronic sinusitis in patients with involvement of multiple sinuses. The 155 patients evaluated had sinusitis of either the maxillary, ethmoid or frontal sinuses (any combination) and had organisms recovered from two to four concomitantly infected sinuses. Similar aerobic, facultatively anaerobic and anaerobic organisms were recovered from all groups of patients. In patients who had organisms isolated from two sinuses and had acute sinusitis, 31 (56 %) of the 55 isolates were found only in a single sinus, and 24 (44 %) were recovered concomitantly from two sinuses. In those with chronic infection 31 (34 %) of the 91 isolates were recovered only from a single sinus, and 60 (66 %) were found concomitantly from two sinuses. Anaerobic bacteria were more often isolated concomitantly from two sinuses (50 of 70) than aerobic and facultatively anaerobic (ten of 21, < 0.05). Similar findings were observed in patients who had organisms isolated from three or four sinuses. β-Lactamase-producing bacteria were more often isolated from patients with chronic infection (58–83 %) as compared to those with acute infections (32–43 %). These findings illustrate that there are differences in the distribution of organisms in single patients who suffer from infections in multiple sinuses and emphasize the importance of obtaining cultures from all infected sinuses.

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2004-09-01
2019-11-13
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References

  1. Brook, I. ( 1981;). Bacteriological features of chronic sinusitis in children. JAMA 246, 967–969.[CrossRef]
    [Google Scholar]
  2. Brook, I. ( 1984;). The role of β-lactamase-producing bacteria in the persistence of streptococcal tonsillar infection. Rev Infect Dis 6, 601–607.[CrossRef]
    [Google Scholar]
  3. Brook, I. & Gober, A. E. ( 1984;). Emergence of β-lactamase-producing aerobic and anaerobic bacteria in the oropharynx of children following penicillin chemotherapy. Clin Pediatr (Phila) 23, 338–341.[CrossRef]
    [Google Scholar]
  4. Brook, I. & Yocum, P. ( 1995;). Bacteriology and β-lactamase activity in ear aspirates of acute otitis media that failed amoxicillin therapy. Pediatr Infect Dis J 14, 805–809.[CrossRef]
    [Google Scholar]
  5. Brook, I. & Gober, A. E. ( 1996;). Prophylaxis with amoxicillin or sulfisoxazole for otitis media: effect on the recovery of penicillin-resistant bacteria from children. Clin Infect Dis 22, 143–145.[CrossRef]
    [Google Scholar]
  6. Brook, I. Yocum, P. & Frazier, E. H. ( 1996;). Bacteriology and β-lactamase activity in acute and chronic maxillary sinusitis. Arch Otolaryngol Head Neck Surg 122, 418–423.[CrossRef]
    [Google Scholar]
  7. Ednie, L. M., Spangler, S. K., Jacobs, M. R. & Appelbaum, P. C. ( 1997;). Susceptibilities of 228 penicillin- and erythromycin-susceptible and -resistant pneumonococci to RU 64004, a new ketolide, compared with susceptibilities to 16 other agents. Antimicrob Agents Chemother 41, 1033–1036.
    [Google Scholar]
  8. Jacobs, M. R. ( 2003;). Worldwide trends in antimicrobial resistance among common respiratory tract pathogens in children. Pediatr Infect Dis J 22 (8 Suppl.), S109–S119.[CrossRef]
    [Google Scholar]
  9. Jousimies-Somer, H. R., Savolainen, S. & Ylikoski J. S. ( 1988;). Bacteriological findings of acute maxillary sinusitis in young adults. J Clin Microbiol 26, 1919–1925.
    [Google Scholar]
  10. Murray, P. R., Baron, E. J., Pfaller, M. A., Tenover, P. C. & Yolken, R. H. ( 1999;). Manual of Clinical Microbiology, 7th edn. Washington, DC: American Society for Microbiology.
  11. Nord, C. E. ( 1995;). The role of anaerobic bacteria in recurrent episodes of sinusitis and tonsillitis. Clin Infect Dis 20, 1512–1524.[CrossRef]
    [Google Scholar]
  12. O'Callaghan, C. H., Morris, A., Kirby, S. M. & Shingler, A. H. ( 1972;). Novel method for detection of β-lactamases by using a chromogenic cephalosporin substrate. Antimicrob Agents Chemother 1, 283–288.[CrossRef]
    [Google Scholar]
  13. Paju, S., Bernstein, J. M., Haase, E. M. & Scannapieco, F. A. ( 2003;). Molecular analysis of bacterial flora associated with chronically inflamed maxillary sinuses. J Med Microbiol 52, 591–597.[CrossRef]
    [Google Scholar]
  14. Summanen, P., Baron, E. J., Citron, D. M., Strong, C. A., Wexler, H. M. & Finegold, S. M. ( 1993;). Wadsworth Anaerobic Bacteriology Manual, 5th edn. Belmont, CA: Star Publishing.
  15. Wexler, H. M. & Finegold, S. M. ( 1998;). Current susceptibility patterns of anaerobic bacteria. Yonsei Med J 39, 495–501.[CrossRef]
    [Google Scholar]
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