Antifungal susceptibility and virulence attributes of animal-derived isolates of complex Free

Abstract

This study aimed to identify strains of the complex isolated from animals, as well as to assess their antifungal susceptibility profile and production of virulence attributes. We used 28 isolates of recovered from clinically healthy animals. The strains were characterized phenotypically, followed by molecular identification of the species through PCR-restriction enzyme analysis. The susceptibility of the strains to amphotericin B, itraconazole, voriconazole, fluconazole and caspofungin was assessed through broth microdilution. Additionally, the ability of the strains to produce biofilm, phospholipases and proteases was analysed. Molecular analysis showed 13 , 10 and five strains. resistance to fluconazole was observed in three strains of and two . . All tested strains were able to form biofilms and 23/28 isolates presented protease production, whilst none was able to produce phospholipases. Our study showed that . and . are the most common species of the . species complex and that these cryptic species present no significant phenotypical differences.

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2014-11-01
2024-03-29
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