1887

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Volume 53, Issue 7

Switches, cross-talk and memory in adherence Free

Abstract

is a successful commensal and pathogen. Its pathogenic diversity stems from the acquisition and expression of multiple virulence-associated loci. Many of the key virulence factors are surface structures involved in adherence and motility. These are important antigens and their expression is limited by phase-variable genetic switches that are considered to act randomly. This review considers the possibility that such stochastic expression within a bacterial population belies sequential or co-ordinate control at the level of the individual bacterium. Co-ordinated expression or cross-talk between virulence loci can lead to a programmed set of events within a bacterium analogous to a simple form of electronic memory that is of benefit during infection.

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2004-07-01
2024-04-18
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Switches, cross-talk and memory in Escherichia coli adherence
J. Med. Microbiol. 53, 585 (2004); https://doi.org/10.1099/jmm.0.05491-0
/content/journal/jmm/10.1099/jmm.0.05491-0
/content/journal/jmm/10.1099/jmm.0.05491-0
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