1887

Abstract

The outer-membrane protein pertactin (Prn) of , and is believed to function as an adhesin and is an important immunogen. The emergence of and . Prn variants has been reported. The aim of this study was to determine whether similar variation is found in Prn and to characterize Finnish clinical isolates that were collected in 1982–2000. Of 76 isolates studied, seven (9 %) were found to have silent and non-silent nucleotide changes. In addition, one (1 %) had eight PQP repeats instead of nine. Three closely related I PFGE patterns were found. Genetic variation of was found to be very limited, suggesting that is a stable organism that is well-adapted to its own ecological niche.

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2003-12-01
2019-11-18
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