Nocardia nova is a rare aetiological pathogen for cutaneous nocardiosis. To the best of our knowledge, this is the first case of N. nova primary cutaneous infection in a kidney transplant recipient. Identification was performed using 16S rRNA and secA1 gene sequence analyses. The patient was not treated successfully by antibiotics alone. Surgical debridement was required for successful treatment.
AntunesJ.,
PachecoD.,
TravassosR.,
SequeiraH.,
FilipeP.,
MarquesM. S.2012; Actinomycetoma of the chest wall attributed to Nocardia nova after reconstructive surgery. Dermatol Online J 18:4[PubMed]
Brown-ElliottB. A.,
BrownJ. M.,
ConvilleP. S.,
WallaceR. J.Jr2006; Clinical and laboratory features of the Nocardia spp. based on current molecular taxonomy. Clin Microbiol Rev 19:259–282 [View Article][PubMed]
CLSI2008Interpretive Criteria for Identification of Bacteria and Fungi by DNA Target Sequencing Approved Guideline. CLSI Document MM18-A Wayne, PA: Clinical Laboratory Standards Institute;
ConvilleP. S.,
WitebskyF. G.2007; Nocardia, Rhodococcus, Gordonia, Actinomadura, Streptomyces, and other aerobic actinomycetes. In Manual of Clinical Microbiology, 9th edn. pp. 515–542 Edited by
MurrayP. R.,
BaronE. J.,
JorgensenJ. H.,
LandryM. L.,
PfallerM. A.
Washington, DC: American Society for Microbiology;
DhingraM.,
KaisthaN.,
BansalN.,
SolankiL. S.,
ChanderJ.,
ThamiG. P.,
van de SandeW. W.2012; Nocardia nova mycetoma over forehead in a lepromatous leprosy patient. Dermatol Online J 18:3[PubMed]
Dodiuk-GadR.,
CohenE.,
ZivM.,
GoldsteinL. H.,
ChazanB.,
ShaferJ.,
SprecherH.,
EliasM.,
KenessY.,
RozenmanD.2010; Cutaneous nocardiosis: report of two cases and review of the literature. Int J Dermatol 49:1380–1385 [View Article][PubMed]
InamadarA. C.,
PalitA.,
PeerapurB. V.,
RaoS. D.2004; Sporotrichoid nocardiosis caused by Nocardia nova in a patient infected with human immunodeficiency virus. Int J Dermatol 43:824–826 [View Article][PubMed]
MuñozJ.,
MirelisB.,
AragónL. M.,
GutiérrezN.,
SánchezF.,
EspañolM.,
EsparciaO.,
GurguíM.,
DomingoP.,
CollP.2007; Clinical and microbiological features of nocardiosis 1997–2003. J Med Microbiol 56:545–550 [View Article][PubMed]
SchiffT. A.,
SanchezM.,
MoyJ.,
KlirsfeldD.,
McNeilM. M.,
BrownJ. M.1993; Cutaneous nocardiosis caused by Nocardia nova occurring in an HIV-infected individual: a case report and review of the literature. J Acquir Immune Defic Syndr 6:849–851[PubMed]
ShimizuA.,
IshikawaO.,
NagaiY.,
MikamiY.,
NishimuraK.2001; Primary cutaneous nocardiosis due to Nocardia nova in a healthy woman. Br J Dermatol 145:154–156 [View Article][PubMed]
TanC. K.,
LaiC. C.,
LinS. H.,
LiaoC. H.,
ChouC. H.,
HsuH. L.,
HuangY. T.,
HsuehP. R.2010; Clinical and microbiological characteristics of Nocardiosis including those caused by emerging Nocardia species in Taiwan, 1998–2008. Clin Microbiol Infect 16:966–972[PubMed][CrossRef]
WallaceR. J.Jr,
BrownB. A.,
TsukamuraM.,
BrownJ. M.,
OnyiG. O.1991; Clinical and laboratory features of Nocardia nova
. J Clin Microbiol 29:2407–2411[PubMed]
ZhiX. Y.,
LiW. J.,
StackebrandtE.2009; An update of the structure and 16S rRNA gene sequence-based definition of higher ranks of the class Actinobacteria, with the proposal of two new suborders and four new families and emended descriptions of the existing higher taxa. Int J Syst Evol Microbiol 59:589–608 [View Article][PubMed]