1887

Abstract

A collection of strains from clinical isolates, healthy individuals and the environment was screened for the presence of virulence factor genes, such as those for collagen-binding protein (), endocarditis antigen (), haemolysin activator (), gelatinase (), aggregation substances ( and ), a surface protein () and two novel putative surface antigens ( and ). Apart from some genes that were present in all strains (, and ), the gene was the most common factor, although its presence did not correlate with its expression. The genes that encode Esp and CylA were never detected in endocarditis isolates, whereas an association was noted between the gene and isolates from urinary tract infection (UTI) and bacteraemia. An aggregation substance gene was always present in commensal strains. As for gelatinase, the presence of the and genes did not correlate completely with their phenotypic expression. Generally, isolates from endocarditis, biliary stents and the environment were equipped with fewer virulence factors than isolates from other sources. UTI strains possessed the highest number of factors.

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2004-01-01
2019-12-07
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