RT Journal Article SR Electronic(1) A1 Dannaoui, Eric A1 Meletiadis, Joseph A1 Tortorano, Anna-Maria A1 Symoens, Françoise A1 Nolard, Nicole A1 Viviani, Maria-Anna A1 Piens, Marie-Antoinette A1 Lebeau, Bernadette A1 Verweij, Paul E. A1 Grillot, Renée A1 and the EBGA NetworkYR 2004 T1 Susceptibility testing of sequential isolates of Aspergillus fumigatus recovered from treated patients JF Journal of Medical Microbiology, VO 53 IS 2 SP 129 OP 134 DO https://doi.org/10.1099/jmm.0.05326-0 PB Microbiology Society, SN 1473-5644, AB Two-hundred sequential Aspergillus fumigatus isolates recovered from 26 immunocompromised patients with invasive aspergillosis or bronchial colonization were tested for their in vitro susceptibility to posaconazole, itraconazole, voriconazole, terbinafine and amphotericin B. Twenty-one patients were treated with amphotericin B and/or itraconazole. Antifungal susceptibilities of the isolates recovered before treatment were not significantly different from those of isolates recovered after the onset of antifungal therapy. The highest MICs were 0.125, 0.5, 0.5, 1 and 1 μg ml−1 for posaconazole, itraconazole, voriconazole, terbinafine and amphotericin B, respectively. It is concluded that the emergence of resistance in A. fumigatus during antifungal therapy with amphotericin B or itraconazole is an uncommon phenomenon., UL https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.05326-0