1887

Abstract

Newborns are rarely infected by extended-spectrum β-lactamase (ESBL)-producing members of the . In a neonatal intensive care unit, 14 newborns were infected or colonized by CTX-M-15-producing . All seven infected patients had underlying medical conditions, and five of them were treated successfully with meropenem, whilst one untreated patient died. Paediatric infections caused by multidrug-resistant ESBL-producing constitute a critical clinical and epidemiological issue.

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2013-04-01
2019-10-23
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References

  1. Cantón R., Oliver A., Coque T. M., Varela M. del C., Pérez-Díaz J. C., Baquero F.. ( 2002;). Epidemiology of extended-spectrum β-lactamase-producing Enterobacter isolates in a Spanish hospital during a 12-year period. . J Clin Microbiol 40:, 1237–1243. [CrossRef][PubMed]
    [Google Scholar]
  2. Carattoli A., Bertini A., Villa L., Falbo V., Hopkins K. L., Threlfall E. J.. ( 2005;). Identification of plasmids by PCR-based replicon typing. . J Microbiol Methods 63:, 219–228. [CrossRef][PubMed]
    [Google Scholar]
  3. CLSI ( 2012;). Performance Standards for Antimicrobial Susceptibility Testing, 22nd Informational Supplement M100-S22. . Wayne, PA:: Clinical and Laboratory Standards Institute;.
  4. Diestra K., Juan C., Curiao T., Moyá B., Miró E., Oteo J., Coque T. M., Pérez-Vázquez M., Campos J.. & other authors ( 2009;). Characterization of plasmids encoding blaESBL and surrounding genes in Spanish clinical isolates of Escherichia coli and Klebsiella pneumoniae. . J Antimicrob Chemother 63:, 60–66. [CrossRef][PubMed]
    [Google Scholar]
  5. Garza-González E., Mendoza Ibarra S. I., Llaca-Díaz J. M., Gonzalez G. M.. ( 2011;). Molecular characterization and antimicrobial susceptibility of extended-spectrum β-lactamase-producing Enterobacteriaceae isolates at a tertiary-care centre in Monterrey, Mexico. . J Med Microbiol 60:, 84–90. [CrossRef][PubMed]
    [Google Scholar]
  6. Hyle E. P., Ferraro M. J., Silver M., Lee H., Hooper D. C.. ( 2010;). Ertapenem-resistant Enterobacteriaceae: risk factors for acquisition and outcomes. . Infect Control Hosp Epidemiol 31:, 1242–1249. [CrossRef][PubMed]
    [Google Scholar]
  7. Iabadene H., Messai Y., Ammari H., Ramdani-Bouguessa N., Lounes S., Bakour R., Arlet G.. ( 2008;). Dissemination of ESBL and Qnr determinants in Enterobacter cloacae in Algeria. . J Antimicrob Chemother 62:, 133–136. [CrossRef][PubMed]
    [Google Scholar]
  8. Kartali G., Tzelepi E., Pournaras S., Kontopoulou C., Kontos F., Sofianou D., Maniatis A. N., Tsakris A.. ( 2002;). Outbreak of infections caused by Enterobacter cloacae producing the integron-associated β-lactamase IBC-1 in a neonatal intensive care unit of a Greek hospital. . Antimicrob Agents Chemother 46:, 1577–1580. [CrossRef][PubMed]
    [Google Scholar]
  9. Manzur A., Tubau F., Pujol M., Calatayud L., Dominguez M. A., Peña C., Sora M., Gudiol F., Ariza J.. ( 2007;). Nosocomial outbreak due to extended-spectrum-β-lactamase-producing Enterobacter cloacae in a cardiothoracic intensive care unit. . J Clin Microbiol 45:, 2365–2369. [CrossRef][PubMed]
    [Google Scholar]
  10. Moriguchi N., Itahashi Y., Tabata N., Yamazumi T., Furuta I., Shibata N., Arakawa Y., Miyata H.. ( 2007;). Outbreak of CTX-M-3-type extended-spectrum β-lactamase-producing Enterobacter cloacae in a pediatric ward. . J Infect Chemother 13:, 263–266. [CrossRef][PubMed]
    [Google Scholar]
  11. Mshana S. E., Gerwing L., Minde M., Hain T., Domann E., Lyamuya E., Chakraborty T., Imirzalioglu C.. ( 2011;). Outbreak of a novel Enterobacter sp. carrying blaCTX-M-15 in a neonatal unit of a tertiary care hospital in Tanzania. . Int J Antimicrob Agents 38:, 265–269.[PubMed]
    [Google Scholar]
  12. Oteo J., Navarro C., Cercenado E., Delgado-Iribarren A., Wilhelmi I., Orden B., García C., Miguelañez S., Pérez-Vázquez M.. & other authors ( 2006;). Spread of Escherichia coli strains with high-level cefotaxime and ceftazidime resistance between the community, long-term care facilities, and hospital institutions. . J Clin Microbiol 44:, 2359–2366. [CrossRef][PubMed]
    [Google Scholar]
  13. Oteo J., Hernández-Almaraz J. L., Gil-Antón J., Vindel A., Fernández S., Bautista V., Campos J.. ( 2010;). Outbreak of VIM-1-carbapenemase-producing Enterobacter cloacae in a pediatric intensive care unit. . Pediatr Infect Dis J 29:, 1144–1146. [CrossRef][PubMed]
    [Google Scholar]
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