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Journal of Medical Microbiology logo Journal of Medical Microbiology

Volume 61, Issue 8

Isolation and characterization of a novel recombinant human adenovirus species D No Access

Abstract

A novel recombinant human adenovirus (HAdV) species D was isolated from the stool of a pharyngitis patient in Japan and genetic characterization was performed by sequencing variable regions between HAdV types. The nucleotide sequences of the penton base gene and loops 1 and 2 in the hexon gene showed 100 % identity with that of the recently identified HAdV-56. Although we observed greatest identity for the entire hexon gene sequence with that of HAdV-56, we noted even greater similarity between the partial nucleotide sequence of the conserved region 4 and that of HAdV-37. Furthermore, the fibre gene and early region 3 sequences were completely identical to that of HAdV-37. These results suggest that the strain is a novel adenovirus related to HAdV-37 and HAdV-56.

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© 2012 SGM
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/content/journal/jmm/10.1099/jmm.0.042176-0
2012-08-01
2025-05-19
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/content/journal/jmm/10.1099/jmm.0.042176-0
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Isolation and characterization of a novel recombinant human adenovirus species D
J. Med. Microbiol. 61, 1097 (2012); https://doi.org/10.1099/jmm.0.042176-0
/content/journal/jmm/10.1099/jmm.0.042176-0
/content/journal/jmm/10.1099/jmm.0.042176-0
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