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Volume 61, Issue 7

Liver cirrhosis as a predisposing condition for Legionnaires’ disease: a report of four laboratory-confirmed cases from China Free

Abstract

Here, we describe four cases of laboratory-confirmed infection. Case 1 was a culture-confirmed case of infection in a patient with liver cirrhosis. Following this, three other liver cirrhosis cases (cases 2–4) were diagnosed with infection as confirmed by quantitative real-time PCR. The cause of the pneumonia was determined as by positive direct fluorescence assay and isolation of the causative agent. The infections were successfully treated by administering appropriate antibiotics. These cases highlight the importance of considering as a cause of pneumonia in patients with liver disease and lung infections. The strain of isolated from Case 1 was characterized as being closely related to strain Philadelphila-1 (ATCC 33152), which is the type strain of the species, belonging to serogroup 1 and sequence type 36 (ST36), and is known to be distributed worldwide. To our knowledge, this is the first report of infection on the Chinese mainland for a decade and highlights the need to raise awareness of diagnostic methods for Legionnaires’ disease in China and the requirement for further epidemiological surveillance strategies to monitor this disease.

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© 2012 SGM
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2012-07-01
2024-04-24
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Liver cirrhosis as a predisposing condition for Legionnaires’ disease: a report of four laboratory-confirmed cases from China
J. Med. Microbiol. 61, 1023 (2012); https://doi.org/10.1099/jmm.0.040170-0
/content/journal/jmm/10.1099/jmm.0.040170-0
/content/journal/jmm/10.1099/jmm.0.040170-0
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