1887

Abstract

Human infection due to , an actinomycete, is rare and the majority of those infections are due to This agent has been implicated in cutaneous, pulmonary, eye and disseminated infections. It has never been isolated from the nose or any nasal infection. We report here a rare case of nasal vestibular abscess due to in an adult diabetic patient. The bacterium was identified on the basis of morphological and biochemical characteristics, and confirmed by sequencing the 16S rRNA and genes. The patient was successfully treated with clarithromycin and levofloxacin. Though infections may be rare, the study highlights that it may cause a wide spectrum of disease manifestations, and laboratories should take care to isolate and identify the easily treatable pathogen.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/jmm.0.038240-0
2012-08-01
2024-03-29
Loading full text...

Full text loading...

/deliver/fulltext/jmm/61/8/1168.html?itemId=/content/journal/jmm/10.1099/jmm.0.038240-0&mimeType=html&fmt=ahah

References

  1. Ajello L., Brown J., Macdonald E., Head E. 1987; Actinomycetoma caused by Nocardiopsis dassonvillei . Arch Dermatol 123:426 [View Article][PubMed]
    [Google Scholar]
  2. Beau F., Bollet C., Coton T., Garnotel E., Drancourt M. 1999; Molecular identification of a Nocardiopsis dassonvillei blood isolate. J Clin Microbiol 37:3366–3368[PubMed]
    [Google Scholar]
  3. Bernatchez H., Lebreux E. 1991; Nocardiopsis dassonvillei recovered from a lung biopsy and a possible cause of extrinsic alveolitis. Clin Microbiol Newsl 6:47–55
    [Google Scholar]
  4. Brocq-Rousseu D. 1904; Sur un streptothrix. Rev Gen Bot 16:219–230
    [Google Scholar]
  5. Euzéby J. P. 2011; Nocardiopsis (Brocq-Rousseau 1904) Meyer 1976, genus. In List of Prokaryotic Names with Standing in Nomenclature http://www.bacterio.cict.fr/n/nocardiopsis.html Accessed July 2011
    [Google Scholar]
  6. Felsenstein J. 1985; Confidence limits on phylogenies: an approach using the bootstrap. Evolution 39:783–791 [View Article]
    [Google Scholar]
  7. Figueiredo R. R., Azevedo A. A., Kós A. O., Tomita S. 2006; Nasal foreign bodies: description of types and complications in 420 cases. Braz J Otorhinolaryngol 72:18–23[PubMed]
    [Google Scholar]
  8. Gombert M. E. 1982; Susceptibility of Nocardia asteroides to various antibiotics, including newer beta-lactams, trimethoprim-sulfamethoxazole, amikacin, and N-formimidoyl thienamycin. Antimicrob Agents Chemother 21:1011–1012[PubMed] [CrossRef]
    [Google Scholar]
  9. González-López M. A., González-Vela M. C., Salas-Venero C. A., Conde R., Val-Bernal J. F. 2011; Cutaneous infection caused by Nocardiopsis dassonvillei presenting with sporotrichoid spread. J Am Acad Dermatol 65:e90–e91 [View Article][PubMed]
    [Google Scholar]
  10. La Scola B., Birtles R. J., Mallet M. N., Raoult D. 1998; Massilia timonae gen. nov., sp. nov., isolated from blood of an immunocompromised patient with cerebellar lesions. J Clin Microbiol 36:2847–2852[PubMed]
    [Google Scholar]
  11. Lechevalier H. A., Lechevalier M. P. 1970; Chemical composition as a criterion in the classification of aerobic actinomycetes. Int J Syst Bacteriol 20:435–443 [View Article]
    [Google Scholar]
  12. Lejbkowicz F., Kudinsky R., Samet L., Belavsky L., Barzilai M., Predescu S. 2005; Identification of Nocardiopsis dassonvillei in a blood sample from a child. Am J Infect Dis 1:1–4 [View Article]
    [Google Scholar]
  13. Liegard H., Landrieu M. 1911; Un cas de mycose conjonctivale. Ann Ocul (Paris) 146:418–426
    [Google Scholar]
  14. Meyer J. 1976; Nocardiopsis, a new genus of the order Actinomycetales . Int J Syst Bacteriol 26:487–493 [View Article]
    [Google Scholar]
  15. Mordarska H., Zakrzewska-Czerwiñska J., Paściak M., Szponar B., Rowiñski S. 1998; Rare, suppurative pulmonary infection caused by Nocardiopsis dassonvillei recognized by glycolipid markers. FEMS Immunol Med Microbiol 21:47–55 [View Article][PubMed]
    [Google Scholar]
  16. Philip A., Roberts G. D. 1984; Nocardiopsis dassonvillei cellulitis of the arm. Clin Microbiol Newsl 6:14–15 [View Article]
    [Google Scholar]
  17. Rainey F. A., Ward-Rainey N., Kroppenstedt R. M., Stackebrandt E. 1996; The genus Nocardiopsis represents a phylogenetically coherent taxon and a distinct actinomycete lineage: proposal of Nocardiopsaceae fam. nov.. Int J Syst Bacteriol 46:1088–1092 [View Article][PubMed]
    [Google Scholar]
  18. Rodríguez-Nava V., Couble A., Devulder G., Flandrois J. P., Boiron P., Laurent F. 2006; Use of PCR-restriction enzyme pattern analysis and sequencing database for hsp65 gene-based identification of Nocardia species. J Clin Microbiol 44:536–546 [View Article][PubMed]
    [Google Scholar]
  19. Saitou N., Nei M. 1987; The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol 4:406–425[PubMed]
    [Google Scholar]
  20. Sindhuphak W., Macdonald E., Head E. 1985; Actinomycetoma caused by Nocardiopsis dassonvillei . Arch Dermatol 121:1332–1334 [View Article][PubMed]
    [Google Scholar]
  21. Singh S. M., Naidu J., Mukerjee S., Malkani A. 1991 Cutaneous infections due to Nocardiopsis dassonvillei (Brocq-rousseau) Meyer 1976, endemic in members of a family up to fifth degree relatives. In: Program and Abstracts of the XI Congress of the International Society for Human and Animal Mycology, abstract PS1.91, p. 85
  22. Tamura K., Nei M., Kumar S. 2004; Prospects for inferring very large phylogenies by using the neighbor-joining method. Proc Natl Acad Sci U S A 101:11030–11035 [View Article][PubMed]
    [Google Scholar]
  23. Tamura K., Dudley J., Nei M., Kumar S. 2007; mega4: Molecular Evolutionary Genetics Analysis (mega) software version 4.0. Mol Biol Evol 24:1596–1599 [View Article][PubMed]
    [Google Scholar]
  24. Tang S.-K., Li W.-J., Dong W., Zhang Y.-G., Xu L.-H., Jiang C.-L. 2003; Studies of the biological characteristics of some halophilic and halotolerant actinomycetes isolated from saline and alkaline soils. Actinomycetologica 17:6–10 [View Article]
    [Google Scholar]
  25. Weisburg W. G., Barns S. M., Pelletier D. A., Lane D. J. 1991; 16S ribosomal DNA amplification for phylogenetic study. J Bacteriol 173:697–703[PubMed]
    [Google Scholar]
  26. Yassin A. F., Rainey F. A., Burghardt J., Gierth D., Ungerechts J., Lux I., Seifert P., Bal C., Schaal K. P. 1997; Description of Nocardiopsis synnemataformans sp. nov., elevation of Nocardiopsis alba subsp. prasina to Nocardiopsis prasina comb. nov., and designation of Nocardiopsis antarctica and Nocardiopsis alborubida as later subjective synonyms of Nocardiopsis dassonvillei . Int J Syst Bacteriol 47:983–988 [View Article][PubMed]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/jmm.0.038240-0
Loading
/content/journal/jmm/10.1099/jmm.0.038240-0
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error