RT Journal Article SR Electronic(1) A1 Tortorano, Anna Maria A1 Prigitano, Anna A1 Dho, Giovanna A1 Grancini, Anna A1 Passera, Marco A1 for the ECMM-FIMUA Study GroupYR 2012 T1 Antifungal susceptibility profiles of Candida isolates from a prospective survey of invasive fungal infections in Italian intensive care units JF Journal of Medical Microbiology, VO 61 IS 3 SP 389 OP 393 DO https://doi.org/10.1099/jmm.0.037895-0 PB Microbiology Society, SN 1473-5644, AB The antifungal susceptibility pattern of 302 Candida isolates collected during an Italian survey on invasive fungal infections in an intensive care setting was investigated. The results were correlated with some epidemiological data and compared with the antifungal profiles obtained in a previous survey. No resistance to echinocandins was detected. The overall resistance levels to fluconazole, posaconazole and voriconazole were 12.6, 6.0 and 7.1 %, respectively. Candida tropicalis and Candida parapsilosis accounted for more than half of all the fluconazole resistant isolates. Reduced susceptibility to fluconazole is not uncommon among isolates (12.3 %) and appears to be increasing, particularly among C. parapsilosis isolates, which showed an increase in resistant isolates from 2 % in the 1990s to 25.8 % in the present study. Routine antifungal susceptibility testing of this species is therefore recommended., UL https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.037895-0