1887

Abstract

is an environmental contaminant that has been rarely associated with clinical infections. Here, two cases of severe sepsis caused by are described in two full-term neonates; one in a female infant with no factors predisposing her to infection and the other in a male infant requiring mechanical ventilation and an intravenous catheter. In both cases, the micro-organism was recovered from repeated blood cultures and was identified using biochemical assays and 16S rRNA gene sequencing. Both infants were successfully treated with vancomycin. This report reveals the potential role of as a bloodstream pathogen during infancy.

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2012-04-01
2024-04-24
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References

  1. Adler A., Gottesman G., Dolfin T., Arnon S., Regev R., Bauer S., Litmanovitz I. 2005; Bacillus species sepsis in the neonatal intensive care unit. J Infect 51:390–395 [View Article][PubMed]
    [Google Scholar]
  2. Banerjee C., Bustamante C. I., Wharton R., Talley E., Wade J. C. 1988; Bacillus infections in patients with cancer. Arch Intern Med 148:1769–1774 [View Article][PubMed]
    [Google Scholar]
  3. Bentur H. N., Dalzell A. M., Riordan F. A. I. 2007; Central venous catheter infection with Bacillus pumilus in an immunocompetent child: a case report. Ann Clin Microbiol Antimicrob 6:12 [View Article][PubMed]
    [Google Scholar]
  4. CLSI. 2010 Methods for antimicrobial dilution and disk susceptibility testing of infrequently isolated or fastidious bacteria; approved guideline, 2nd edn, M45–A2. Wayne, PA: Clinical and Laboratory Standards Institute
  5. Cotton D. J., Gill V. J., Marshall D. J., Gress J., Thaler M., Pizzo P. A. 1987; Clinical features and therapeutic interventions in 17 cases of Bacillus bacteremia in an immunosuppressed patient population. J Clin Microbiol 25:672–674[PubMed]
    [Google Scholar]
  6. Drobniewski F. A. 1993; Bacillus cereus and related species. Clin Microbiol Rev 6:324–338[PubMed]
    [Google Scholar]
  7. Farhat H., Chachaty E., Antoun S., Nitenberg G., Zahar J.-R. 2008; [Two cases of Bacillus infection and immunodepression]. Med Mal Infect 38:612–614 (in French) [View Article][PubMed]
    [Google Scholar]
  8. Farrar W. E. Jr 1963; Serious infections due to “non-pathogenic” organisms of the genus Bacillus. Review of their status as pathogens. Am J Med 34:134–141 [View Article][PubMed]
    [Google Scholar]
  9. From C., Hormazabal V., Granum P. E. 2007; Food poisoning associated with pumilacidin-producing Bacillus pumilus in rice. Int J Food Microbiol 115:319–324 [View Article][PubMed]
    [Google Scholar]
  10. Galanos J., Perera S., Smith H., O’Neal D., Sheorey H., Waters M. J. 2003; Bacteremia due to three Bacillus species in a case of Munchausen’s syndrome. J Clin Microbiol 41:2247–2248 [View Article][PubMed]
    [Google Scholar]
  11. Hilliard N. J., Schelonka R. L., Waites K. B. 2003; Bacillus cereus bacteremia in a preterm neonate. J Clin Microbiol 41:3441–3444 [View Article][PubMed]
    [Google Scholar]
  12. Logan N. A., Berkeley R. C. W. 1984; Identification of Bacillus strains using the API system. J Gen Microbiol 130:1871–1882[PubMed]
    [Google Scholar]
  13. Logan N. A., Popovic T., Hoffmaster A. 2009; Bacillus and other aerobic endospore-forming bacteria. In Manual of Clinical Microbiology, 9th edn. pp. 455–473 Edited by Murray P. R., Baron E. J., Jorgensen J. H., Landry M. L., Pfaller M. A. Washington, DC: American Society for Microbiology;
    [Google Scholar]
  14. Mellmann A., Cloud J., Maier T., Keckevoet U., Ramminger I., Iwen P., Dunn J., Hall G., Wilson D. other authors 2008; Evaluation of matrix-assisted laser desorption ionization-time-of-flight mass spectrometry in comparison to 16S rRNA gene sequencing for species identification of nonfermenting bacteria. J Clin Microbiol 46:1946–1954 [View Article][PubMed]
    [Google Scholar]
  15. Ozkocaman V., Ozcelik T., Ali R., Ozkalemkas F., Ozkan A., Ozakin C., Akalin H., Ursavas A., Coskun F. other authors 2006; Bacillus spp. among hospitalized patients with haematological malignancies: clinical features, epidemics and outcomes. J Hosp Infect 64:169–176 [View Article][PubMed]
    [Google Scholar]
  16. Patrick C. C., Langston C., Baker C. J. 1989; Bacillus species infections in neonates. Rev Infect Dis 11:612–615 [View Article][PubMed]
    [Google Scholar]
  17. Schelonka R. L., Infante A. J. 1998; Neonatal immunology. Semin Perinatol 22:2–14 [View Article][PubMed]
    [Google Scholar]
  18. Suominen I., Andersson M. A., Andersson M. C., Hallaksela A. M., Kämpfer P., Rainey F. A., Salkinoja-Salonen M. 2001; Toxic Bacillus pumilus from indoor air, recycled paper pulp, Norway spruce, food poisoning outbreaks and clinical samples. Syst Appl Microbiol 24:267–276 [View Article][PubMed]
    [Google Scholar]
  19. Tena D., Martinez-Torres J. A., Perez-Pomata M. T., Sáez-Nieto J. A., Rubio V., Bisquert J. 2007; Cutaneous infection due to Bacillus pumilus: report of 3 cases. Clin Infect Dis 44:e40–e42 [View Article][PubMed]
    [Google Scholar]
  20. Weber D. J., Saviteer S. M., Rutala W. A., Thomann C. A. 1989; Clinical significance of Bacillus species isolated from blood cultures. South Med J 82:705–709 [View Article][PubMed]
    [Google Scholar]
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