1887

Abstract

Illicit drug control has been on the global agenda for more than a century. Infections have long been recognized as one of the most serious complications of drug abuse. Drug users are susceptible to pulmonary, endovascular, skin and soft tissue, bone and joint, and sexually transmitted infections caused by a wide range of bacterial, viral, fungal and protozoal pathogens. In addition, injection drug users are at increased risk for parenterally acquired infections such as human immunodeficiency virus, hepatitis B virus, hepatitis C virus, tetanus and malaria. Factors related to drug use, such as unsterile injection practices, contaminated drug paraphernalia and drug adulterants, increase the exposure to microbial pathogens. Illicit drugs also affect several components of the complex immune system and thus modulate host immunity. In addition, lifestyle practices such as multiple sexual partners, overcrowded housing arrangements and malnutrition serve as co-factors in increasing the risk of infection. In this review we present an overview of the unique aspects of microbial pathogenesis, immune modulation and common infections associated with drug use. We have restricted the definition of drug abuse to the use of illegal drugs (such as opiates, marijuana, cocaine, heroin and amphetamines), not including alcohol and nicotine.

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2011-04-01
2024-03-28
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References

  1. Abdala N., Carney J. M., Durante A. J., Klimov N., Ostrovski D., Somlai A. M., Kozlov A., Heimer R. 2003; Estimating the prevalence of syringe-borne and sexually transmitted diseases among injection drug users in St Petersburg, Russia. Int J STD AIDS 14:697–703 [CrossRef]
    [Google Scholar]
  2. Aboltins C. A., Allen P., Daffy J. R. 2005; Fungal endophthalmitis in intravenous drug users injecting buprenorphine contaminated with oral Candida species. Med J Aust 182:427
    [Google Scholar]
  3. Aceijas C., Stimson G. V., Hickman M., Rhodes T. on behalf of the United Nations Reference Group on HIV/AIDS Prevention and Care among IDU in Developing and Transitional Countries; 2004; Global overview of injecting drug use and HIV infection among injecting drug users. AIDS 18:2295–2303 [CrossRef]
    [Google Scholar]
  4. Aguilar G. L., Blumenkrantz M. S., Egbert P. R., McCulley J. P. 1979; Candida endophthalmitis after intravenous drug abuse. Arch Ophthalmol 97:96–100 [CrossRef]
    [Google Scholar]
  5. Akbulut D., Grant K. A., McLauchlin J. 2005; Improvement in laboratory diagnosis of wound botulism and tetanus among injecting illicit-drug users by use of real-time PCR assays for neurotoxin gene fragments. J Clin Microbiol 43:4342–4348 [CrossRef]
    [Google Scholar]
  6. Albini T. A., Sun R. L., Holz E. R., Khurana R. N., Rao N. A. 2007; Lemon juice and candida endophthalmitis in crack-cocaine misuse. Br J Ophthalmol 91:702–703 [CrossRef]
    [Google Scholar]
  7. Al-Rawahi G. N., Schreader A. G., Porter S. D., Roscoe D. L., Gustafson R., Bryce E. A. 2008; Methicillin-resistant Staphylococcus aureus nasal carriage among injection drug users: six years later. J Clin Microbiol 46:477–479 [CrossRef]
    [Google Scholar]
  8. Anon. 1876; Tetanus after hypodermic injection of morphia. Lancet ii 873:
    [Google Scholar]
  9. Aral S. O., St Lawrence J. S. 2002; The ecology of sex work and drug use in Saratov Oblast, Russia. Sex Transm Dis 29:798–805 [CrossRef]
    [Google Scholar]
  10. Astemborski J., Vlahov D., Warren D., Solomon L., Nelson K. E. 1994; The trading of sex for drugs or money and HIV seropositivity among female intravenous drug users. Am J Public Health 84:382–387 [CrossRef]
    [Google Scholar]
  11. Atkinson S. R., Paul J., Sloan E., Curtis S., Miller R. 2009; The emergence of meticillin-resistant Staphylococcus aureus among injecting drug users. J Infect 58:339–345 [CrossRef]
    [Google Scholar]
  12. Baker J. E., Crawford G. P. 1978; Malaria: a new facet of heroin addiction in Australia. Med J Aust 2:427–428
    [Google Scholar]
  13. Barry J., Ward M., Cotter S., Macdiarmada J., Hannan M., Sweeney B., Grant K. A., McKeown P. 2009; Botulism in injecting drug users. Dublin, Ireland, November–December: 2008 Euro Surveill 14:19082
    [Google Scholar]
  14. Bartlett J. G. 1991; Clostridium tetani. In Infectious Diseases pp 1580–1583 Edited by Gorbach S. L., Bartlett J. G., Blacklow N. R. Philadelphia, PA: W. B. Saunders;
    [Google Scholar]
  15. Bassetti S., Battegay M. 2004; Staphylococcus aureus infections in injection drug users: risk factors and prevention strategies. Infection 32:163–169 [CrossRef]
    [Google Scholar]
  16. Bassols A. M., Santos R. A., Rohde L. A., Pechansky F. 2007; Exposure to HIV in Brazilian adolescents: the impact of psychiatric symptomatology. Eur Child Adolesc Psychiatry 16:236–242 [CrossRef]
    [Google Scholar]
  17. Bastos F. I., Barcellos C., Lowndes C. M., Friedman S. R. 1999; Co-infection with malaria and HIV in injecting drug users in Brazil: a new challenge to public health?. Addiction 94:1165–1174 [CrossRef]
    [Google Scholar]
  18. Bastos F. I., Lowndes C. M., Derrico M., Castello-Branco L. R., Linhares-De-Carvalho M. I., Oelemann W., Bernier F., Morgado M. G., Yoshida C. F. other authors 2000; Sexual behaviour and infection rates for HIV, blood-borne and sexually transmitted infections among patients attending drug treatment centres in Rio de Janeiro, Brazil. Int J STD AIDS 11:383–392 [CrossRef]
    [Google Scholar]
  19. Basu D. 2010; Overview of substance abuse and hepatitis C virus infecFtion and co-infections in India. J Neuroimmune Pharmacol 5:496–506 [CrossRef]
    [Google Scholar]
  20. Beeching N. J., Crowcroft N. S. 2005; Tetanus in injecting drug users. BMJ 330:208–209 [CrossRef]
    [Google Scholar]
  21. Bick R. L., Anhalt J. E. Jr 1971; Malaria transmission among narcotic addicts. A report of ten cases and review of the literature. Calif Med 115:56–58
    [Google Scholar]
  22. Biggam A. G. 1929; Malignant malaria associated with the administration of heroin intravenously. Trans R Soc Trop Med Hyg 23:147–153 [CrossRef]
    [Google Scholar]
  23. Bisbe J., Miro J. M., Latorre X., Moreno A., Mallolas J., Gatell J. M., de la Bellacasa J. P., Soriano E. 1992; Disseminated candidiasis in addicts who use brown heroin: report of 83 cases and review. Clin Infect Dis 15:910–923 [CrossRef]
    [Google Scholar]
  24. Blázquez R., Pinedo A., Cosín J., Miralles P., Lacruz C., Bouza E. 1996; Nonsurgical cure of isolated cerebral mucormycosis in an intravenous drug user. Eur J Clin Microbiol Infect Dis 15:598–599 [CrossRef]
    [Google Scholar]
  25. Bleck T. P. 2005; Clostridium botulinum (botulism). In Mandell, Douglas and Bennett's Principles and Practice of Infectious Diseases pp 2822–2828 Edited by Mandell G. L., Bennett J. E., Dolin R. Philadelphia, PA: Churchill Livingstone;
    [Google Scholar]
  26. Blomberg J., Moestrup T., Frimand J., Hansson B. G., Krogsgaard K., Grillner L., Nordenfelt E. 1994; HTLV-I and -II in intravenous drug users from Sweden and Denmark. Scand J Infect Dis 26:23–26 [CrossRef]
    [Google Scholar]
  27. Böhlen L. M., Mühlemann K., Dubuis O., Aebi C., Täuber M. G. 2000; Outbreak among drug users caused by a clonal strain of group A streptococcus. Emerg Infect Dis 6:175–179
    [Google Scholar]
  28. Boll K. L., Jurik A. G. 1990; Sternal osteomyelitis in drug addicts. J Bone Joint Surg Br 72:328–329
    [Google Scholar]
  29. Booth M. G., Hood J., Brooks T. J. G., Hart A. Health Protection Scotland Anthrax Clinical Network; 2010; Anthrax infection in drug users. Lancet 375:1345–1346
    [Google Scholar]
  30. Botsford K. B., Weinstein R. A., Nathan C. R., Kabins S. A. 1985; Selective survival in pentazocine and tripelennamine of Pseudomonas aeruginosa serotype O11 from drug addicts. J Infect Dis 151:209–216 [CrossRef]
    [Google Scholar]
  31. Brancós M. A., Peris P., Miró J. M., Monegal A., Gatell J. M., Mallolas J., Mensa J., García S., Muñoz-Gomez J. 1991; Septic arthritis in heroin addicts. Semin Arthritis Rheum 21:81–87 [CrossRef]
    [Google Scholar]
  32. Brazier J. S., Duerden B. I., Hall V., Salmon J. E., Hood J., Brett M. M., McLauchlin J., George R. C. 2002; Isolation and identification of Clostridium spp. from infections associated with the injection of drugs: experiences of a microbiological investigation team. J Med Microbiol 51:985–989
    [Google Scholar]
  33. Brazier J. S., Morris T. E., Duerden B. I. 2003; Heat and acid tolerance of Clostridium novyi type A spores and their survival prior to preparation of heroin for injection. Anaerobe 9:141–144 [CrossRef]
    [Google Scholar]
  34. Brett M. M., Hallas G., Mpamugo O. 2004; Wound botulism in the UK and Ireland. J Med Microbiol 53:555–561 [CrossRef]
    [Google Scholar]
  35. Brown J. D., Khoa N. Q. 1975; Fatal falciparum malaria among narcotic injectors. Am J Trop Med Hyg 24:729–733
    [Google Scholar]
  36. Bucardo J., Brouwer K. C., Magis-Rodríguez C., Ramos R., Fraga M., Perez S. G., Patterson T. L., Strathdee S. A. 2005; Historical trends in the production and consumption of illicit drugs in Mexico: implications for the prevention of blood borne infections. Drug Alcohol Depend 79:281–293 [CrossRef]
    [Google Scholar]
  37. Buchy P., Follézou J. Y., Lien T. X., An T. T. N., Tram L. T., Tri D. V., Cuong N. M., Glaziou P., Chien B. T. 2003; Serological study of toxoplasmosis in Vietnam in a population of drug users (Ho Chi Minh city) and pregnant women (Nha Trang. Bull Soc Pathol Exot 96:46–47
    [Google Scholar]
  38. Burnette-Curley D., Marciano-Cabral F., Fischer-Stenger K., Cabral G. A. 1993; Δ-9-Tetrahydrocannabinol inhibits cell contact-dependent cytotoxicity of Bacillus Calmétte-Guérin-activated macrophages. Int J Immunopharmacol 15:371–382
    [Google Scholar]
  39. Bussiere J. L., Adler M. W., Rogers T. J., Eisenstein T. K. 1992; Differential effects of morphine and naltrexone on the antibody response in various mouse strains. Immunopharmacol Immunotoxicol 14:657–673 [CrossRef]
    [Google Scholar]
  40. Cabral G. A., Marciano-Cabral F. 2004; Cannabinoid-mediated exacerbation of brain infection by opportunistic amebae. J Neuroimmunol 147:127–130 [CrossRef]
    [Google Scholar]
  41. Cabral G. A., Staab A. 2005; Effects on the immune system. Handb Exp Pharmacol 168:385–423
    [Google Scholar]
  42. CDC 1990; Aspergillus endophthalmitis in intravenous-drug users – Kentucky. MMWR Morb Mortal Wkly Rep 39:48–49
    [Google Scholar]
  43. CDC 1991; Crack cocaine use among persons with tuberculosis – Contra Costa County, California, 1987–1990. MMWR Morb Mortal Wkly Rep 40:485–489
    [Google Scholar]
  44. CDC 2000; Unexplained illness and death among injecting-drug users –. Glasgow, Scotland; Dublin, Ireland; and England: April–June 2000 MMWR Morb Mortal Wkly Rep 49:489–492
    [Google Scholar]
  45. Chao C. C., Sharp B. M., Pomeroy C., Filice G. A., Peterson P. K. 1990; Lethality of morphine in mice infected with Toxoplasma gondii . J Pharmacol Exp Ther 252:605–609
    [Google Scholar]
  46. Chau T. T. H., Mai N. T. H., Phu N. H., Luxemburger C., Chuong L. V., Loc P. P., Trang T. T. M., Vinh H., Cuong B. M. & other authors (2002. Malaria in injection drug abusers in Vietnam. Clin Infect Dis 34:1317–1322 [CrossRef]
    [Google Scholar]
  47. Christensen P. B., Krarup H. B., Niesters H. G., Norder H., Schaffalitzky de Muckadell O. B., Jeune B., Georgsen J. 2001; Outbreak of hepatitis B among injecting drug users in Denmark. J Clin Virol 22:133–141 [CrossRef]
    [Google Scholar]
  48. Christie B. 2010; Heroin contaminated with anthrax has killed 11 people. BMJ 340:c937 [CrossRef]
    [Google Scholar]
  49. Chuo C. Y., Fu Y. C., Lu Y. M., Chen J. C., Shen W. J., Yang C. H., Chen C. Y. 2007; Spinal infection in intravenous drug abusers. J Spinal Disord Tech 20:324–328 [CrossRef]
    [Google Scholar]
  50. Cohen A. L., Shuler C., McAllister S., Fosheim G. E., Brown M. G., Abercrombie D., Anderson K., McDougal L. K., Drenzek C. other authors 2007; Methamphetamine use and methicillin-resistant Staphylococcus aureus skin infections. Emerg Infect Dis 13:1707–1713 [CrossRef]
    [Google Scholar]
  51. Cooke F. J., Gkrania-Klotsas E., Howard J. C., Stone M., Kearns A. M., Ganner M., Carmichael A. J., Brown N. M. 2010; Clinical, molecular and epidemiological description of a cluster of community-associated methicillin-resistant Staphylococcus aureus isolates from injecting drug users with bacteraemia. Clin Microbiol Infect 16:921–926 [CrossRef]
    [Google Scholar]
  52. Craven D. E., Rixinger A. I., Goularte T. A., McCabe W. R. 1986; Methicillin-resistant Staphylococcus aureus bacteremia linked to intravenous drug abusers using a “shooting gallery”. Am J Med 80:770–776 [CrossRef]
    [Google Scholar]
  53. Cross T. J., Rizzi P., Horner M., Jolly A., Hussain M. J., Smith H. M., Vergani D., Harrison P. M. 2008; The increasing prevalence of hepatitis delta virus (HDV) infection in South London. J Med Virol 80:277–282 [CrossRef]
    [Google Scholar]
  54. Cruz I., Morales M. A., Noguer I., Rodríguez A., Alvar J. 2002; Leishmania in discarded syringes from intravenous drug users. Lancet 359:1124–1125 [CrossRef]
    [Google Scholar]
  55. Curtis S. J., Tanna A., Russell H. H., Efstratiou A., Paul J., Cubbon M., Sriskandan S. 2007; Invasive group A streptococcal infection in injecting drug users and non-drug users in a single UK city. J Infect 54:422–426 [CrossRef]
    [Google Scholar]
  56. Dancer S. J., McNair D., Finn P., Kolsto A.-B. 2002; Bacillus cereus cellulitis from contaminated heroin. J Med Microbiol 51:278–281
    [Google Scholar]
  57. Darban H., Watson R. R., Alak J., Thomas N. 1993; Cocaine facilitation of cryptosporidiosis by murine AIDS in male and female C57/BL/6 mice. Adv Exp Med Biol 335:143–151
    [Google Scholar]
  58. Des Jarlais D. C., Arasteh K., Perlis T., Hagan H., Abdul-Quader A., Heckathorn D. D., McKnight C., Bramson H., Nemeth C. other authors 2007; Convergence of HIV seroprevalence among injecting and non-injecting drug users in New York City. AIDS 21:231–235 [CrossRef]
    [Google Scholar]
  59. Deutscher M., Perlman D. C. 2008; Why some injection drug users lick their needles: a preliminary survey. Int J Drug Policy 19:342–345 [CrossRef]
    [Google Scholar]
  60. Drew S. I., Carter B. M., Nathanson D. S., Terasaki P. I. 1980; Levamisole-associated neutropenia and autoimmune granulocytotoxins. Ann Rheum Dis 39:59–63 [CrossRef]
    [Google Scholar]
  61. Dunbar N. M., Harruff R. C. 2007; Necrotizing fasciitis: manifestations, microbiology and connection with black tar heroin. J Forensic Sci 52:920–923 [CrossRef]
    [Google Scholar]
  62. Efstratiou A., Emery M., Lamagni T. L., Tanna A., Warner M., George R. C. 2003; Increasing incidence of group A streptococcal infections amongst injecting drug users in England and Wales. J Med Microbiol 52:525–526 [CrossRef]
    [Google Scholar]
  63. Elliott J. H., O'Day D. M., Gutow G. S., Podgorski S. F., Akrabawi P. 1979; Mycotic endophthalmitis in drug abusers. Am J Ophthalmol 88:66–72 [CrossRef]
    [Google Scholar]
  64. Ernst A. A., Martin D. H. 1993; High syphilis rates among cocaine abusers identified in an emergency department. Sex Transm Dis 20:66–69 [CrossRef]
    [Google Scholar]
  65. Fäh F., Zimmerli W., Jordi M., Schoenenberger R. A. 2002; Septic deep venous thrombosis in intravenous drug users. Swiss Med Wkly 132:386–392
    [Google Scholar]
  66. Farley T. A., Hadler J. L., Gunn R. A. 1990; The syphilis epidemic in Connecticut: relationship to drug use and prostitution. Sex Transm Dis 17:163–168 [CrossRef]
    [Google Scholar]
  67. Ferguson R., Feeney C., Chirurgi V. A. 1993; Enterobacter agglomerans -associated cotton fever. Arch Intern Med 153:2381–2382 [CrossRef]
    [Google Scholar]
  68. Fisher D. G., Fenaughty A. M., Paschane D. M., Cagle H. H. 2000; Alaska native drug users and sexually transmitted disease: results of a five-year study. Am Indian Alsk Native Ment Health Res 9:47–57 [CrossRef]
    [Google Scholar]
  69. Fleisch F., Zbinden R., Vanoli C., Ruef C. 2001; Epidemic spread of a single clone of methicillin-resistant Staphylococcus aureus among injection drug users in Zurich, Switzerland. Clin Infect Dis 32:581–586 [CrossRef]
    [Google Scholar]
  70. Friedman H. 1996; Drugs of abuse as possible co-factors in AIDS progression: summary of panel discussion. Adv Exp Med Biol 402:225–228
    [Google Scholar]
  71. Friedman L. N., Williams M. T., Singh T. P., Frieden T. R. 1996; Tuberculosis, AIDS, and death among substance abusers on welfare in New York City. N Engl J Med 334:828–833 [CrossRef]
    [Google Scholar]
  72. Friedman H., Newton C., Klein T. W. 2003; Microbial infections, immunomodulation, and drugs of abuse. Clin Microbiol Rev 16:209–219 [CrossRef]
    [Google Scholar]
  73. Friedman H., Pross S., Klein T. W. 2006; Addictive drugs and their relationship with infectious diseases. FEMS Immunol Med Microbiol 47:330–342 [CrossRef]
    [Google Scholar]
  74. Friedmann C. T., Dover A. S., Roberto R. R., Kearns O. A. 1973; A malaria epidemic among heroin users. Am J Trop Med Hyg 22:302–307
    [Google Scholar]
  75. Fucci N. 2007; Unusual adulterants in cocaine seized on Italian clandestine market. Forensic Sci Int 172:e1 [CrossRef]
    [Google Scholar]
  76. Funke G., Altwegg M., Frommelt L., von Graevenitz A. 1999; Emergence of related nontoxigenic Corynebacterium diphtheriae biotype mitis strains in Western Europe. Emerg Infect Dis 5:477–480 [CrossRef]
    [Google Scholar]
  77. Gaing A. A., Corbalan F., Weinberger J. 1992; Phycomycosis (mucormycosis) in differential diagnosis of cerebral mass lesions in intravenous drug users. Mt Sinai J Med 59:69–71
    [Google Scholar]
  78. Gilbert M., MacDonald J., Gregson D., Siushansian J., Zhang K., Elsayed S., Laupland K., Louie T., Hope K. other authors 2006; Outbreak in Alberta of community-acquired (USA300) methicillin-resistant Staphylococcus aureus in people with a history of drug use, homelessness or incarceration. CMAJ 175:149–154 [CrossRef]
    [Google Scholar]
  79. Gilla G., Pérez-Trallero E., Sáenz-Dominguez J. R., Esparza H., Otero F. 1994; Tetanus immunity among intravenous drug users in Guipuzcoa (Basque Country, Spain). AIDS 8:271–272 [CrossRef]
    [Google Scholar]
  80. Gonzalez Garcia J. J., Arnalich F., Peña J. M., Garcia-Alegria J. J., Garcia Fernandez F., Jimenez Herraez C., Vazquez J. J. 1986; An outbreak of Plasmodium vivax malaria among heroin users in Spain. Trans R Soc Trop Med Hyg 80:549–552 [CrossRef]
    [Google Scholar]
  81. Gordon R. J., Lowy F. D. 2005; Bacterial infections in drug users. N Engl J Med 353:1945–1954 [CrossRef]
    [Google Scholar]
  82. Gruner E., Opravil M., Altwegg M., von Graevenitz A. 1994; Nontoxigenic Corynebacterium diphtheriae isolated from intravenous drug users. Clin Infect Dis 18:94–96 [CrossRef]
    [Google Scholar]
  83. Gubler J., Huber-Schneider C., Gruner E., Altwegg M. 1998; An outbreak of nontoxigenic Corynebacterium diphtheriae infection: single bacterial clone causing invasive infection among Swiss drug users. Clin Infect Dis 27:1295–1298 [CrossRef]
    [Google Scholar]
  84. Hagan H., Pouget E. R., Williams I. T., Garfein R. L., Strathdee S. A., Hudson S. M., Latka M. H., Ouellet L. J. 2010; Attribution of hepatitis C virus seroconversion risk in young injection drug users in 5 US cities. J Infect Dis 201:378–385 [CrossRef]
    [Google Scholar]
  85. Hahn J. A., Page-Shafer K., Lum P. J., Bourgois P., Stein E., Evans J. L., Busch M. P., Tobler L. H., Phelps B., Moss A. R. 2002; Hepatitis C virus seroconversion among young injection drug users: relationships and risks. J Infect Dis 186:1558–1564 [CrossRef]
    [Google Scholar]
  86. Hahné S. J. M., White J. M., Crowcroft N. S., Brett M. M., George R. C., Beeching N. J., Roy K., Goldberg D. 2006; Tetanus in injecting drug users. United Kingdom. Emerg Infect Dis 12:709–710 [CrossRef]
    [Google Scholar]
  87. Harrison D. W., Walls R. M. 1990; “Cotton fever”: a benign febrile syndrome in intravenous drug abusers. J Emerg Med 8:135–139 [CrossRef]
    [Google Scholar]
  88. Hasemann L. 1961; How long can spores of American foulbrood live?. Am Bee J 101:298–299
    [Google Scholar]
  89. Hemingway D. M., Balfour A. E., McCartney A. C., Leiberman D. P. 1992; Streptococcus milleri and complex groin abscesses in intravenous drug abusers. Scott Med J 37:116–117
    [Google Scholar]
  90. Hirst L. W., Thomas J. V., Green W. R. 2005; Endophthalmitis. In Mandell, Douglas and Bennett's Principles and Practice of Infectious Diseases pp 760–767 Edited by Mandell G. L., Bennett J. E., Dolin R. Philadelphia, PA: Churchill Livingstone;
    [Google Scholar]
  91. Hogg G. G., Strachan J. E., Huayi L., Beaton S. A., Robinson P. M., Taylor K. 1996; Non-toxigenic Corynebacterium diphtheriae biovar gravis : evidence for an invasive clone in a south-eastern Australian community. Med J Aust 164:72–75
    [Google Scholar]
  92. Holder M. K., Mong J. A. 2010; Methamphetamine enhances paced mating behaviors and neuroplasticity in the medial amygdala of female rats. Horm Behav 58:519–525 [CrossRef]
    [Google Scholar]
  93. Hopkins R. J., Rothman M., Fiore A., Goldblum S. E. 1994; Cerebral mucormycosis associated with intravenous drug use: three case reports and review. Clin Infect Dis 19:1133–1137 [CrossRef]
    [Google Scholar]
  94. Huang H., Cohen S. H., King J. H., Monchaud C., Nguyen H., Flynn N. M. 2008; Injecting drug use and community-associated methicillin-resistant Staphylococcus aureus infection. Diagn Microbiol Infect Dis 60:347–350 [CrossRef]
    [Google Scholar]
  95. Huber G. L., Pochay V. E., Pereira W., Shea J. W., Hinds W. C., First M. W., Sornberger G. C. 1980; Marijuana, tetrahydrocannabinol, and pulmonary antibacterial defenses. Chest 77:403–410 [CrossRef]
    [Google Scholar]
  96. Hussey H. H., Katz S. 1950; Infections resulting from narcotic addiction; report of 102 cases. Am J Med 9:186–193 [CrossRef]
    [Google Scholar]
  97. Jittiwutikarn J., Thongsawat S., Suriyanon V., Maneekarn N., Celentano D., Razak M. H., Srirak N., Vongchak T., Kawichai S. other authors 2006; Hepatitis C infection among drug users in northern Thailand. Am J Trop Med Hyg 74:1111–1116
    [Google Scholar]
  98. Jones J. A., Salmon J. E., Djuretic T., Nichols G., George R. C., Gill O. N., Brazier J. S., Brett M. M., Duerden B. I. other authors 2002; An outbreak of serious illness and death among injecting drug users in England during 2000. J Med Microbiol 51:978–984
    [Google Scholar]
  99. Jose B., Friedman S. R., Neaigus A. 1993; Possible parenteral transmission of syphilis among drug injectors. In 121st Annual Meeting of the American Public Health Association San Francisco, CA: October 1993
    [Google Scholar]
  100. Julander I., Petrini B. 1997; Penicillium marneffei infection in a Swedish HIV-infected immunodeficient narcotic addict. Scand J Infect Dis 29:320–322 [CrossRef]
    [Google Scholar]
  101. Kalka-Moll W. M., Aurbach U., Schaumann R., Schwarz R., Seifert H. 2007; Wound botulism in injection drug users. Emerg Infect Dis 13:942–943 [CrossRef]
    [Google Scholar]
  102. Käll K. I., Olin R. G. 1990; HIV status and changes in risk behaviour among intravenous drug users in Stockholm 1987–1988. AIDS 4:153–158 [CrossRef]
    [Google Scholar]
  103. Kaplan S. S. 1974; Pseudomonas disc space infection in an occasional heroin user. Ariz Med 31:916–919
    [Google Scholar]
  104. Keyashian K., Malani P. N. 2007; Endophthalmitis associated with intravenous drug use. South Med J 100:1219–1220 [CrossRef]
    [Google Scholar]
  105. Kirmani N., Tuazon C. U., Alling D. 1980; Carriage rate of Staphylococcus aureus among patients receiving allergy injections. Ann Allergy 45:235–237
    [Google Scholar]
  106. Klein T. W., Newton C., Larsen K., Lu L., Perkins I., Nong L., Friedman H. 2003; The cannabinoid system and immune modulation. J Leukoc Biol 74:486–496 [CrossRef]
    [Google Scholar]
  107. Kluytmans J., van Belkum A., Verbrugh H. 1997; Nasal carriage of Staphylococcus aureus : epidemiology, underlying mechanisms, and associated risks. Clin Microbiol Rev 10:505–520
    [Google Scholar]
  108. Kudrow D. B., Henry D. A., Haake D. A., Marshall G., Mathisen G. E. 1988; Botulism associated with Clostridium botulinum sinusitis after intranasal cocaine abuse. Ann Intern Med 109:984–985 [CrossRef]
    [Google Scholar]
  109. Lalitha M. K., Anandi V., Walter N., Devadatta J. O., Pulimood B. M. 1988; Primary anthrax presenting as an injection “abscess”. Indian J Pathol Microbiol 31:254–256
    [Google Scholar]
  110. Lamagni T. L., Neal S., Keshishian C., Hope V., George R., Duckworth G., Vuopio-Varkila J., Efstratiou A. 2008; Epidemic of severe Streptococcus pyogenes infections in injecting drug users in the UK, 2003–2004. Clin Microbiol Infect 14:1002–1009 [CrossRef]
    [Google Scholar]
  111. Léchot P., Schaad H. J., Graf S., Täuber M., Mühlemann K. 2001; Group A streptococcus clones causing repeated epidemics and endemic disease in intravenous drug users. Scand J Infect Dis 33:41–46 [CrossRef]
    [Google Scholar]
  112. Lee H. H., Weiss S. H., Brown L. S., Mildvan D., Shorty V., Saravolatz L., Chu A., Ginzburg H. M., Markowitz N. other authors 1990; Patterns of HIV-1 and HTLV-I/II in intravenous drug abusers from the middle atlantic and central regions of the USA. J Infect Dis 162:347–352 [CrossRef]
    [Google Scholar]
  113. Leen C. L. S., Brettle R. P. 1991; Fungal infections in drug users. J Antimicrob Chemother 28:S83–S96
    [Google Scholar]
  114. Leonhardt K. K., Gentile F., Gilbert B. P., Aiken M. 1994; A cluster of tuberculosis among crack house contacts in San Mateo County, California. Am J Public Health 84:1834–1836 [CrossRef]
    [Google Scholar]
  115. Levin M. H., Weinstein R. A., Nathan C., Selander R. K., Ochman H., Kabins S. A. 1984; Association of infection caused by Pseudomonas aeruginosa serotype O11 with intravenous abuse of pentazocine mixed with tripelennamine. J Clin Microbiol 20:758–762
    [Google Scholar]
  116. Levine D. P., Brown P. V. 2005; Infections in injection drug users. In Mandell, Douglas, Bennett's Principles and Practice of Infectious Diseases pp 3462–3476 Edited by Mandell G. L., Bennett J. E., Dolin R. Philadelphia, PA: Churchill Livingstone;
    [Google Scholar]
  117. Levine D. P., Crane L. R., Zervos M. J. 1986; Bacteremia in narcotic addicts at the Detroit Medical Center. II. Infectious endocarditis: a prospective comparative study. Rev Infect Dis 8:374–396 [CrossRef]
    [Google Scholar]
  118. Levine O. S., Vlahov D., Koehler J., Cohn S., Spronk A. M., Nelson K. E. 1995; Seroepidemiology of hepatitis B virus in a population of injecting drug users. Association with drug injection patterns. Am J Epidemiol 142:331–341
    [Google Scholar]
  119. Levinson A., Marske R. L., Shein M. K. 1955; Tetanus in heroin addicts. J Am Med Assoc 157:658–660 [CrossRef]
    [Google Scholar]
  120. Li Y., Wang X., Tian S., Guo C.-J., Douglas S. D., Ho W.-Z. 2002; Methadone enhances human immunodeficiency virus infection of human immune cells. J Infect Dis 185:118–122 [CrossRef]
    [Google Scholar]
  121. Li Y., Zhang T., Douglas S. D., Lai J.-P., Xiao W.-D., Pleasure D. E., Ho W.-Z. 2003; Morphine enhances hepatitis C virus (HCV) replicon expression. Am J Pathol 163:1167–1175 [CrossRef]
    [Google Scholar]
  122. Li J. R., Gong R. Y., Li Y. P., Bai Y., You F., Deng S. 2010; Research on HIV/ Toxoplasma gondii co-infection and cytokine levels among intravenous drug users. Parasite Immunol 32:161–164 [CrossRef]
    [Google Scholar]
  123. Lloyd-Smith E., Hull M. W., Tyndall M. W., Zhang R., Wood E., Montaner J. S. G., Kerr T., Romney M. G. 2010; Community-associated methicillin-resistant Staphylococcus aureus is prevalent in wounds of community-based injection drug users. Epidemiol Infect 138:713–720 [CrossRef]
    [Google Scholar]
  124. López-Cortés L, Lozano de León F, Gómez-Mateos J. M., Sánchez-Porto A, Obrador C. 1989; Tick-borne relapsing fever in intravenous drug abusers. J Infect Dis 159:804 [CrossRef]
    [Google Scholar]
  125. Lowes P. D. 1966 The Genesis of International Narcotics Control Geneva: Librairie Droz;
    [Google Scholar]
  126. Lowy F. D., Miller M. 2002; New methods to investigate infectious disease transmission and pathogenesis – Staphylococcus aureus disease in drug users. Lancet Infect Dis 2:605–612 [CrossRef]
    [Google Scholar]
  127. Ma L., Guo Y., Yuan L., Huang Y., Sun J., Qu S., Yu X., Meng Z., He X. other authors 2009; Phenotypic and genotypic characterization of human immunodeficiency virus type 1 CRF07_BC strains circulating in the Xinjiang Province of China. Retrovirology 6:45 [CrossRef]
    [Google Scholar]
  128. Maayan S., Dan M., Marlink R., Chen Y. M. 1992; HTLV among Israeli intravenous drug abusers. Int J Epidemiol 21:995–997 [CrossRef]
    [Google Scholar]
  129. MacFarlane A. S., Peng X., Meissler J. J. Jr, Rogers T. J., Geller E. B., Adler M. W., Eisenstein T. K. 2000; Morphine increases susceptibility to oral Salmonella typhimurium infection. J Infect Dis 181:1350–1358 [CrossRef]
    [Google Scholar]
  130. Mahfoud Z., Kassak K., Kreidieh K., Shamra S., Ramia S. 2010; Distribution of hepatitis C virus genotypes among injecting drug users in Lebanon. Virol J 7:96 [CrossRef]
    [Google Scholar]
  131. Markowitz N., Hansen N. I., Wilcosky T. C., Hopewell P. C., Glassroth J., Kvale P. A., Mangura B. T., Osmond D., Wallace J. M. other authors 1993; Tuberculin and anergy testing in HIV-seropositive and HIV-seronegative persons. Ann Intern Med 119:185–193 [CrossRef]
    [Google Scholar]
  132. Mathur M. L., Chaudhary R. C. 1996; Increased risk of tuberculosis in opium addicts. Indian J Med Sci 50:365–367
    [Google Scholar]
  133. Matsumoto R. R., McCracken K. A., Pouw B., Zhang Y., Bowen W. D. 2002; Involvement of sigma receptors in the behavioral effects of cocaine: evidence from novel ligands and antisense oligodeoxynucleotides. Neuropharmacology 42:1043–1055 [CrossRef]
    [Google Scholar]
  134. McCarthy L., Wetzel M., Sliker J. K., Eisenstein T. K., Rogers T. J. 2001; Opioids, opioid receptors, and the immune response. Drug Alcohol Depend 62:111–123 [CrossRef]
    [Google Scholar]
  135. McCree D. H., Cosgrove S., Stratford D., Valway S., Keller N., Vega-Hernandez J., Jenison S. A. 2010; Sexual and drug use risk behaviors of long-haul truck drivers and their commercial sex contacts in New Mexico. Public Health Rep 125:52–60
    [Google Scholar]
  136. McCurdy S. A., Ross M. W., Williams M. L., Kilonzo G. P., Leshabari M. T. 2010; Flashblood: blood sharing among female injecting drug users in Tanzania. Addiction 105:1062–1070 [CrossRef]
    [Google Scholar]
  137. McElroy P. D., Rothenberg R. B., Varghese R., Woodruff R., Minns G. O., Muth S. Q., Lambert L. A., Ridzon R. 2003; A network-informed approach to investigating a tuberculosis outbreak: implications for enhancing contact investigations. Int J Tuberc Lung Dis 7:S486–S493
    [Google Scholar]
  138. McGregor R. B. 2005; Corynebacterium diphtheriae . In Mandell, Douglas and Bennett's Principles and Practice of Infectious Diseases pp 1865–1872 Edited by Mandell G. L., Bennett J. E., Dolin R. Philadelphia, PA: Churchill Livingstone;
    [Google Scholar]
  139. McGuigan C. C., Penrice G. M., Gruer L., Ahmed S., Goldberg D., Black M., Salmon J. E., Hood J. 2002; Lethal outbreak of infection with Clostridium novyi type A and other spore-forming organisms in Scottish injecting drug users. J Med Microbiol 51:971–977
    [Google Scholar]
  140. McLauchlin J., Mithani V., Bolton F. J., Nichols G. L., Bellis M. A., Syed Q., Thomson R. P., Ashton J. R. 2002; An investigation into the microflora of heroin. J Med Microbiol 51:1001–1008
    [Google Scholar]
  141. Micozzi M. S., Wetli C. V. 1985; Intravenous amphetamine abuse, primary cerebral mucormycosis, and acquired immunodeficiency. J Forensic Sci 30:504–510
    [Google Scholar]
  142. Mishkin E. M., Cabral G. A. 1985; Delta-9-tetrahydrocannabinol decreases host resistance to herpes simplex virus type 2 vaginal infection in the B6C3F1 mouse. J Gen Virol 66:2539–2549 [CrossRef]
    [Google Scholar]
  143. Monk A. B., Curtis S., Paul J., Enright M. C. 2004; Genetic analysis of Staphylococcus aureus from intravenous drug user lesions. J Med Microbiol 53:223–227 [CrossRef]
    [Google Scholar]
  144. Morahan P. S., Klykken P. C., Smith S. H., Harris L. S., Munson A. E. 1979; Effects of cannabinoids on host resistance to Listeria monocytogenes and herpes simplex virus. Infect Immun 23:670–674
    [Google Scholar]
  145. Morrow R., Wong B., Finkelstein W. E., Sternberg S. S., Armstrong D. 1983; Aspergillosis of the cerebral ventricles in a heroin abuser. Case report and review of the literature. Arch Intern Med 143:161–164 [CrossRef]
    [Google Scholar]
  146. Mullick R., Sengupta S., Sarkar K., Chakrabarti S. 2010; Molecular characterization of tat gene and long terminal repeat region of human immunodeficiency virus type-1 detected among the injecting drug users (IDUs) of Manipur, India: identification of BC recombinants. Virus Res 147:195–201 [CrossRef]
    [Google Scholar]
  147. Munckhof W. J., Konstantinos A., Wamsley M., Mortlock M., Gilpin C. 2003; A cluster of tuberculosis associated with use of a marijuana water pipe. Int J Tuberc Lung Dis 7:860–865
    [Google Scholar]
  148. Murphy E. L., DeVita D., Liu H., Vittinghoff E., Leung P., Ciccarone D. H., Edlin B. R. 2001; Risk factors for skin and soft-tissue abscesses among injection drug users: a case-control study. Clin Infect Dis 33:35–40 [CrossRef]
    [Google Scholar]
  149. Neaigus A., Gyarmathy V. A., Zhao M., Miller M., Friedman S. R., Des Jarlais D. C. 2007; Sexual and other noninjection risks for HBV and HCV seroconversions among noninjecting heroin users. J Infect Dis 195:1052–1061 [CrossRef]
    [Google Scholar]
  150. Nelson K. E., Vlahov D., Cohn S., Odunmbaku M., Lindsay A., Antohony J. C., Hook E. W. III 1991; Sexually transmitted diseases in a population of intravenous drug users: association with seropositivity to the human immunodeficiency virus (HIV). J Infect Dis 164:457–463 [CrossRef]
    [Google Scholar]
  151. Newton C. A., Klein T. W., Friedman H. 1994; Secondary immunity to Legionella pneumophila and Th1 activity are suppressed by delta-9-tetrahydrocannabinol injection. Infect Immun 62:4015–4020
    [Google Scholar]
  152. Nguyen T. V., Khuu N. V., Truong P. H., Nguyen A. P., Truong L. X., Detels R. 2009; Correlation between HIV and sexual behavior, drug use, trichomoniasis and candidiasis among female sex workers in a Mekong Delta province of Vietnam. AIDS Behav 13:873–880 [CrossRef]
    [Google Scholar]
  153. Odds F. C., Palacio-Hernanz A., Cuadra J., Sanchéz J. 1987; Disseminated Candida infection syndrome in heroin addicts – dominance of a single Candida albicans biotype. J Med Microbiol 23:275–277 [CrossRef]
    [Google Scholar]
  154. Oeltmann J. E., Oren E., Haddad M. B., Lake L., Harrington T. A., Ijaz K., Narita M. 2006; Tuberculosis outbreak in marijuana users. Seattle, Washington: 2004 Emerg Infect Dis 12:1156–1159 [CrossRef]
    [Google Scholar]
  155. Oeltmann J. E., Kammerer J. S., Pevzner E. S., Moonan P. K. 2009; Tuberculosis and substance abuse in the United States, 1997–2006. Arch Intern Med 169:189–197 [CrossRef]
    [Google Scholar]
  156. Olopoenia L. A., Mody V., Reynolds M. 1994; Eikenella corrodens endocarditis in an intravenous drug user: case report and literature review. J Natl Med Assoc 86:313–315
    [Google Scholar]
  157. Pacifici R., Zuccaro P., Pichini S., Roset P. N., Poudevida S., Farré M., Segura J., De la Torre R. 2003; Modulation of the immune system in cannabis users. JAMA 289:1929–1931 [CrossRef]
    [Google Scholar]
  158. Panasiak W., Gumułka S., Kobus M., Luczak M. 1990; The influence of morphine on development of HSV-1 and M-MSV virus infection in mice. Acta Microbiol Pol 39:215–218
    [Google Scholar]
  159. Panda S., Chatterjee A., Bhattacharya S. K., Manna B., Singh P. N., Sarkar S., Naik T. N., Chakrabarti S., Detels R. 2000; Transmission of HIV from injecting drug users to their wives in India. Int J STD AIDS 11:468–473 [CrossRef]
    [Google Scholar]
  160. Panessa C., Hill W. D., Giles E., Yu A., Harvard S., Butt G., Andonov A., Krajden M., Osiowy C. 2009; Genotype D amongst injection drug users with acute hepatitis B virus infection in British Columbia. J Viral Hepat 16:64–73 [CrossRef]
    [Google Scholar]
  161. Paradise L. J., Friedman H. 1993; Syphilis and drugs of abuse. Adv Exp Med Biol 335:81–87
    [Google Scholar]
  162. Pascual F. B., McGinley E. L., Zanardi L. R., Cortese M. M., Murphy T. V. 2003; Tetanus surveillance – United States, 1998–2000. MMWR Surveill Summ 52:1–8
    [Google Scholar]
  163. Passaro D. J., Werner S. B., McGee J., Mac Kenzie W. R., Vugia D. J. 1998; Wound botulism associated with black tar heroin among injecting drug users. JAMA 279:859–863 [CrossRef]
    [Google Scholar]
  164. Peng X., Cebra J. J., Adler M. W., Meissler J. J. Jr, Cowan A., Feng P., Eisenstein T. K. 2001; Morphine inhibits mucosal antibody responses and TGF- β mRNA in gut-associated lymphoid tissue following oral cholera toxin in mice. J Immunol 167:3677–3681 [CrossRef]
    [Google Scholar]
  165. Perlman D. C., Salomon N., Perkins M. P., Yancovitz S., Paone D., Des Jarlais D. C. 1995; Tuberculosis in drug users. Clin Infect Dis 21:1253–1264 [CrossRef]
    [Google Scholar]
  166. Petrosillo N., Pellicelli A. M., Cicalini S., Conte A., Goletti D., Palmieri F. 2001; Endocarditis caused by Aspergillus species in injection drug users. Clin Infect Dis 33:e97–e99 [CrossRef]
    [Google Scholar]
  167. Petrosillo N., Viale P., Nicastri E., Arici C., Bombana E., Casella A., Cristini F., De Gennaro M., Dodi F. other authors 2002; Nosocomial bloodstream infections among human immunodeficiency virus-infected patients: incidence and risk factors. Clin Infect Dis 34:677–685 [CrossRef]
    [Google Scholar]
  168. Phillips T. R., Billaud J. N., Henriksen S. J. 2000; Methamphetamine and HIV-1: potential interactions and the use of the FIV/cat model. J Psychopharmacol 14:244–250 [CrossRef]
    [Google Scholar]
  169. Pineda J. A., Macías J., Morillas F., Fernandez-Ochoa J., Cara J., de La Rosa R., Mira J. A., Martín-Sánchez J., González M. other authors 2001; Evidence of increased risk for Leishmania infantum infection among HIV-seronegative intravenous drug users from southern Spain. Eur J Clin Microbiol Infect Dis 20:354–357
    [Google Scholar]
  170. Platt J. J., Labate C. 1976 Heroin Addiction: Theory, Research, and Treatment New York: Wiley;
    [Google Scholar]
  171. Proust B., Dubois F., Bacq Y., Le Pogam S., Rogez S., Levillain R., Goudeau A. 2000; Two successive hepatitis C virus infections in an intravenous drug user. J Clin Microbiol 38:3125–3127
    [Google Scholar]
  172. Quagliarello B., Cespedes C., Miller M., Toro A., Vavagiakis P., Klein R. S., Lowy F. D. 2002; Strains of Staphylococcus aureus obtained from drug-use networks are closely linked. Clin Infect Dis 35:671–677 [CrossRef]
    [Google Scholar]
  173. Quellet L. J., Bailey S. L. 2003; HCV transmission and the sharing of cookers, cotton filters, and rinse water. In Abstracts of the National HIV Prevention Conference. Atlanta, GA, July 2003 abstract no. W0–A1104 Atlanta, GA: Centers for Disease Control and Prevention;
    [Google Scholar]
  174. Radun D., Bernard H., Altmann M., Schöneberg I., Bochat V., van Treeck U., Rippe R. M., Grunow R., Elschner M. other authors 2010; Preliminary case report of fatal anthrax in an injecting drug user in North-Rhine-Westphalia, Germany, December 2009. Euro Surveill 15:19464
    [Google Scholar]
  175. Ramsay C. N., Stirling A., Smith J., Hawkins G., Brooks T., Hood J., Penrice G., Browning L. M., Ahmed S. other authors 2010; An outbreak of infection with Bacillus anthracis in injecting drug users in Scotland. Euro Surveill 15:19465
    [Google Scholar]
  176. Ranjana K. H., Priyokumar K., Singh T. J., Gupta ChC., Sharmila L., Singh P. N., Chakrabarti A. 2002; Disseminated Penicillium marneffei infection among HIV-infected patients in Manipur State, India. J Infect 45:268–271 [CrossRef]
    [Google Scholar]
  177. Reichman L. B., Felton C. P., Edsall J. R. 1979; Drug dependence, a possible new risk factor for tuberculosis disease. Arch Intern Med 139:337–339 [CrossRef]
    [Google Scholar]
  178. Reyes M. P., Ali A., Mendes R. E., Biedenbach D. J. 2009; Resurgence of pseudomonas endocarditis in Detroit, 2006-2008. Medicine (Baltimore 88:294–301 [CrossRef]
    [Google Scholar]
  179. Rieg S., Bauer T. M., Peyerl-Hoffmann G., Held J., Ritter W., Wagner D., Kern W. V., Serr A. 2010; Paenibacillus larvae bacteremia in injection drug users. Emerg Infect Dis 16:487–489 [CrossRef]
    [Google Scholar]
  180. Ringertz S. H., Høiby E. A., Jensenius M., Maehlen J., Caugant D. A., Myklebust A., Fossum K. 2000; Injectional anthrax in a heroin skin-popper. Lancet 356:1574–1575 [CrossRef]
    [Google Scholar]
  181. Robert-Guroff M., Weiss S. H., Giron J. A., Jennings A. M., Ginzburg H. M., Margolis I. B., Blattner W. A., Gallo R. C. 1986; Prevalence of antibodies to HTLV-I, -II, and -III in intravenous drug abusers from an AIDS endemic region. JAMA 255:3133–3137 [CrossRef]
    [Google Scholar]
  182. Rolfs R. T., Goldberg M., Sharrar R. G. 1990; Risk factors for syphilis: cocaine use and prostitution. Am J Public Health 80:853–857 [CrossRef]
    [Google Scholar]
  183. Ross M. W., Hwang L. Y., Zack C., Bull L., Williams M. L. 2002; Sexual risk behaviours and STIs in drug abuse treatment populations whose drug of choice is crack cocaine. Int J STD AIDS 13:769–774 [CrossRef]
    [Google Scholar]
  184. Roth M. D., Tashkin D. P., Choi R., Jamieson B. D., Zack J. A., Baldwin G. C. 2002; Cocaine enhances human immunodeficiency virus replication in a model of severe combined immunodeficient mice implanted with human peripheral blood leukocytes. J Infect Dis 185:701–705 [CrossRef]
    [Google Scholar]
  185. Salloum A., Rao S., Havasi A., Miljkovic G., Amoateng-Adjepong Y. 2004; Aspergillus rib and vertebral osteomyelitis in a former intravenous drug user. Am J Med 116:208–209 [CrossRef]
    [Google Scholar]
  186. Sanders-Buell E., Bose M., Nasir A., Todd C. S., Stanekzai M. R., Tovanabutra S., Scott P. T., Strathdee S. A., Tjaden J. other authors 2010; Distinct circulating recombinant HIV-1 strains among injecting drug users and sex workers in Afghanistan. AIDS Res Hum Retroviruses 26:605–608 [CrossRef]
    [Google Scholar]
  187. Sarkar S., Das N., Panda S., Naik T. N., Sarkar K., Singh B. C., Ralte J. M., Aier S. M., Tripathy S. P. 1993; Rapid spread of HIV among injecting drug users in north-eastern states of India. Bull Narc 45:91–105
    [Google Scholar]
  188. Scheidegger C., Zimmerli W. 1989; Infectious complications in drug addicts: seven-year review of 269 hospitalized narcotics abusers in Switzerland. Rev Infect Dis 11:486–493 [CrossRef]
    [Google Scholar]
  189. Scheidegger C., Pietrzak J., Frei R. 1993; Methadone diluted with contaminated orange juice or raspberry syrup as a potential source of disseminated candidiasis in drug abusers. Eur J Clin Microbiol Infect Dis 12:229–231 [CrossRef]
    [Google Scholar]
  190. Shah S. M., Shapshak P., Rivers J. E., Stewart R. V., Weatherby N. L., Xin K.-Q., Page J. B., Chitwood D. D., Mash D. C. other authors 1996; Detection of HIV-1 DNA in needle/syringes, paraphernalia, and washes from shooting galleries in Miami: a preliminary laboratory report. J Acquir Immune Defic Syndr Hum Retrovirol 11:301–306 [CrossRef]
    [Google Scholar]
  191. Shankland G. S., Richardson M. D. 1989; Possible role of preserved lemon juice in the epidemiology of candida endophthalmitis in heroin addicts. Eur J Clin Microbiol Infect Dis 8:87–89 [CrossRef]
    [Google Scholar]
  192. Shekar R., Rice T. W., Zierdt C. H., Kallick C. A. 1985; Outbreak of endocarditis caused by Pseudomonas aeruginosa serotype O11 among pentazocine and tripelennamine abusers in Chicago. J Infect Dis 151:203–208 [CrossRef]
    [Google Scholar]
  193. Shragg T. 1978; “Cotton fever” in narcotic addicts. JACEP 7:279–280 [CrossRef]
    [Google Scholar]
  194. Sidney S., Beck J. E., Tekawa I. S., Quesenberry C. P., Friedman G. D. 1997; Marijuana use and mortality. Am J Public Health 87:585–590 [CrossRef]
    [Google Scholar]
  195. Siegel L. 1986; AIDS: relationship to alcohol and other drugs. J Subst Abuse Treat 3:271–274 [CrossRef]
    [Google Scholar]
  196. Silpa M., D'Angelo J. 1980; Eikenella corrodens infections in drug abusers. Ann Intern Med 92:871
    [Google Scholar]
  197. Silva M. B., Andrade T. M., Silva L. K., Rodart I. F., Lopes G. B., Carmo T. M., Zarife M. A., Dourado I., Reis M. G. 2010; Prevalence and genotypes of hepatitis C virus among injecting drug users from Salvador-BA, Brazil. Mem Inst Oswaldo Cruz 105:299–303 [CrossRef]
    [Google Scholar]
  198. Stark K., Bienzle U., Vonk R., Guggenmoos-Holzmann I. 1997; History of syringe sharing in prison and risk of hepatitis B virus, hepatitis C virus, and human immunodeficiency virus infection among injecting drug users in Berlin. Int J Epidemiol 26:1359–1366 [CrossRef]
    [Google Scholar]
  199. Stevenson J., Tannahill M., Biggs V. 2001; An outbreak of acute hepatitis B infection among injecting drug users in Inverclyde, Scotland. Commun Dis Public Health 4:60–63
    [Google Scholar]
  200. Strathdee S. A., Stockman J. K. 2010; Epidemiology of HIV among injecting and non-injecting drug users: current trends and implications for interventions. Curr HIV/AIDS Rep 7:99–106 [CrossRef]
    [Google Scholar]
  201. Strathdee S. A., Case P., Lozada R., Mantsios A. R., Alvelais J., Pu M., Brouwer K. C., Miller C. L., Patterson T. L. 2008a; The color of meth: is it related to adverse health outcomes? An exploratory study in Tijuana, Mexico. Am J Addict 17:111–115 [CrossRef]
    [Google Scholar]
  202. Strathdee S. A., Lozada R., Ojeda V. D., Pollini R. A., Brouwer K. C., Vera A., Cornelius W., Nguyen L., Magis-Rodriguez C. & other authors (2008b). Differential effects of migration and deportation on HIV infection among male and female injection drug users in Tijuana, Mexico. PLoS ONE 3:e2690 [CrossRef]
    [Google Scholar]
  203. Swisher L. A., Roberts J. R., Glynn M. J. 1994; Needle licker's osteomyelitis. Am J Emerg Med 12:343–346
    [Google Scholar]
  204. Thomas D. L., Vlahov D., Solomon L., Cohn S., Taylor E., Garfein R., Nelson K. E. 1995; Correlates of hepatitis C virus infections among injection drug users. Medicine (Baltimore) 74:212–220 [CrossRef]
    [Google Scholar]
  205. Thompson S. C., Boughton C. R., Dore G. J. 2003; Blood-borne viruses and their survival in the environment: is public concern about community needlestick exposures justified?. Aust N Z J Public Health 27:602–607 [CrossRef]
    [Google Scholar]
  206. Tubaro E., Borelli G., Croce C., Cavallo G., Santiangeli C. 1983; Effect of morphine on resistance to infection. J Infect Dis 148:656–666 [CrossRef]
    [Google Scholar]
  207. UNODC 2009; World Drug Report. Vienna: : United Nations Office on Drugs and Crime
  208. van Houdt R., Sonder G. J., Dukers N. H. T. M., Bovee L. P. M. J., van den Hoek A., Coutinho R. A., Bruisten S. M. 2007; Impact of a targeted hepatitis B vaccination program in Amsterdam, The Netherlands. Vaccine 25:2698–2705 [CrossRef]
    [Google Scholar]
  209. van Houdt R., van den Berg C. H., Stolte I. G., Bruisten S. M., Dukers N. H., Bakker M., Wolthers K. C., Prins M., Coutinho R. A. 2009; Two decades of hepatitis B infections among drug users in Amsterdam: are they still a high-risk group ? . J Med Virol811163–1169 [CrossRef]
    [Google Scholar]
  210. Verma A., Brozman B., Petito C. K. 2006; Isolated cerebral mucormycosis: report of a case and review of the literature. J Neurol Sci 240:65–69 [CrossRef]
    [Google Scholar]
  211. Villano S. A., Vlahov D., Nelson K. E., Lyles C. M., Cohn S., Thomas D. L. 1997; Incidence and risk factors for hepatitis C among injection drug users in Baltimore. Maryland. J Clin Microbiol 35:3274–3277
    [Google Scholar]
  212. Viviani M. A., Tortorano A. M., Rizzardini G., Quirino T., Kaufman L., Padhye A. A., Ajello L. 1993; Treatment and serological studies of an Italian case of penicilliosis marneffei contracted in Thailand by a drug addict infected with the human immunodeficiency virus. Eur J Epidemiol 9:79–85 [CrossRef]
    [Google Scholar]
  213. Webster G., Barnes E., Brown D., Dusheiko G. 2000; HCV genotypes – role in pathogenesis of disease and response to therapy. Baillieres Best Pract Res Clin Gastroenterol 14:229–240 [CrossRef]
    [Google Scholar]
  214. Werner S. B., Passaro D., McGee J., Schechter R., Vugia D. J. 2000; Wound botulism in California, 1951-1998: recent epidemic in heroin injectors. Clin Infect Dis 31:1018–1024 [CrossRef]
    [Google Scholar]
  215. Williams M. L., Elwood W. N., Weatherby N. L., Bowen A. M., Zhao Z., Saunders L. A., Montoya I. D. 1996; An assessment of the risks of syphilis and HIV infection among a sample of not-in-treatment drug users in Houston, Texas. AIDS Care 8:671–682 [CrossRef]
    [Google Scholar]
  216. Wilson A. P. R. 1995; The return of Corynebacterium diphtheriae : the rise of non-toxigenic strains. J Hosp Infect 30:S306–S312 [CrossRef]
    [Google Scholar]
  217. Zamani S., Radfar R., Nematollahi P., Fadaie R., Meshkati M., Mortazavi S., Sedaghat A., Ono-Kihara M., Kihara M. 2010; Prevalence of HIV/HCV/HBV infections and drug-related risk behaviours amongst IDUs recruited through peer-driven sampling in Iran. Int J Drug Policy 21:493–500 [CrossRef]
    [Google Scholar]
  218. Zhu N. Y., Legatt D. F., Turner A. R. 2009; Agranulocytosis after consumption of cocaine adulterated with levamisole. Ann Intern Med 150:287–289 [CrossRef]
    [Google Scholar]
  219. Zuber P. L., Gruner E., Altwegg M., von Graevenitz A. 1992; Invasive infection with non-toxigenic Corynebacterium diphtheriae among drug users. Lancet 339:1359
    [Google Scholar]
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