1887

Abstract

A young, previously healthy and immunocompetent patient was transferred to our hospital to recover a suspected worm from his gall bladder. Although the diagnosis of infection could not be confirmed, the patient suffered from cholecystitis. To our surprise, the respiratory situation of the patient deteriorated within 24 h under antibiotic therapy and he had to be transferred to the intensive care unit for mechanical respiration. Human cytomegalovirus (HCMV) was isolated directly from a bronchoalveolar lavage (BAL) sample, and DNA was detected by PCR in an enrichment culture of the same BAL sample. Serology for HCMV and clearly supported a primary/post-primary infection for both agents (IgM detection, increase of IgG titres and, in the case of HCMV, a low avidity index of only 22 %). Therefore, we assumed that a rare HCMV and coinfection was the aetiology of the fulminant pneumonia. Under broad antibiotic and antiviral treatment, the situation of the patient improved only very slowly.

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2010-08-01
2019-10-20
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