1887

Journal of Medical Microbiology

Volume 59, Issue 7

Multilocus variable-number tandem repeat analysis of O1 El Tor strains harbouring classical toxin B Free

Abstract

Atypical O1 strains – hybrid strains (strains that cannot be classified either as El Tor or classical biotype) and altered strains (El Tor biotype strains that produce classical cholera toxin) – are currently prevalent in Asia and Africa. A total of 74 hybrid and altered strains that harboured classical cholera toxin were investigated by multilocus variable-number tandem repeat analysis (MLVA). The results showed that the hybrid/altered strains could be categorized into three groups and that they were distant from the El Tor strain responsible for the seventh cholera pandemic. Hybrid/altered strains with a tandem repeat of the classical CTX prophage on the small chromosome were divided into two MLVA groups (group I: Mozambique/Bangladesh group; group III: Vietnam group), and altered strains with the RS1–CTX prophage containing the El Tor type and classical on the large chromosome were placed in two MLVA groups (group II: India/Bangladesh group; group III: India/Vietnam group).

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  • Published Online:
Keyword(s): CT, cholera toxin and MLVA, multilocus variable-number tandem repeat analysis
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2010-07-01
2020-08-14
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Multilocus variable-number tandem repeat analysis of Vibrio cholerae O1 El Tor strains harbouring classical toxin B
J. Med. Microbiol. 59, 763 (2010); https://doi.org/10.1099/jmm.0.017939-0
/content/journal/jmm/10.1099/jmm.0.017939-0
/content/journal/jmm/10.1099/jmm.0.017939-0
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