1887

Abstract

Congenital tuberculosis (TB) remains a rare disease but is fatal if untreated. Early detection is difficult because of the non-specific nature of the symptoms in TB during pregnancy and infancy. This report summarizes a case of congenital TB in a very premature infant, born at 25 weeks gestation. Miliary TB was diagnosed in the mother when the neonate was 20 days old. Antituberculous therapy allowed a rapid improvement in the mother. The infant died at 27 days old. A Beijing genotype strain of was isolated both in the mother, from pulmonary and urine specimens, and in the infant, from peritoneal fluid.

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2010-06-01
2024-04-25
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References

  1. Beitzke H. 1935; About congenital tuberculosis infection. Ergeb Ges Tuberk Forsch 7:1–30 (in German
    [Google Scholar]
  2. Berk D. R., Sylvester K. G. 2004; Congenital tuberculosis presenting as progressive liver dysfunction. Pediatr Infect Dis J 23:78–80 [CrossRef]
    [Google Scholar]
  3. Cantwell M. F., Shehab Z. M., Costello A. M., Sands L., Green W. F., Ewing E. P. Jr, Valway S. E., Onorato I. M. 1994; Congenital tuberculosis. N Engl J Med 330:1051–1054 [CrossRef]
    [Google Scholar]
  4. Chang M. L., Jou S. T., Wang C. R., Chung M. T., Lai S. H., Wong K. S., Huang Y. C., Chou Y. H. 2005; Connatal tuberculosis in a very premature infant. Eur J Pediatr 164:244–247 [CrossRef]
    [Google Scholar]
  5. Glynn J. R., Whiteley J., Bifani P. J., Kremer K., Van Soolingen D. 2002; Worldwide occurrence of Beijing/W strains of Mycobacterium tuberculosis : a systematic review. Emerg Infect Dis 8:843–849 [CrossRef]
    [Google Scholar]
  6. Hassan G., Qureshi W., Kadri S. M. 2006; Congenital tuberculosis. JK Science 8:193–194
    [Google Scholar]
  7. Lillebaek T., Andersen A. B., Dirksen A., Glynn J. R., Kremer K. 2003; Mycobacterium tuberculosis Beijing genotype. Emerg Infect Dis 9:1553–1557 [CrossRef]
    [Google Scholar]
  8. Mazars E., Lesjean S., Banuls A.-L., Gilbert M., Vincent V., Gicquel B., Tibayrenc M., Locht C., Supply P. 2001; High-resolution minisatellite-based typing as a portable approach to global analysis of Mycobacterium tuberculosis molecular epidemiology. Proc Natl Acad Sci U S A 98:1901–1906 [CrossRef]
    [Google Scholar]
  9. Ormerod P. 2001; Tuberculosis in pregnancy and the puerperium. Thorax 56:494–499 [CrossRef]
    [Google Scholar]
  10. Pal P., Ghosh A. 2008; Congenital tuberculosis: late manifestation of the maternal infection. Indian J Pediatr 75:516–518 [CrossRef]
    [Google Scholar]
  11. Patel S., DeSantis E. R. H. 2008; Treatment of congenital tuberculosis. Am J Health Syst Pharm 65:2027–2031 [CrossRef]
    [Google Scholar]
  12. Stähelin-Massik J., Carrel T., Duppenthaler A., Zeilinger G., Gnehm H. E. 2002; Congenital tuberculosis in a premature infant. Swiss Med Wkly 132:598–602
    [Google Scholar]
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