1887

Abstract

This study was designed to determine the genetic basis of florfenicol and ceftiofur resistance in isolates recovered from French cattle. In these isolates, ceftiofur resistance was conferred by located on three distinct conjugative plasmids on a specific DNA fragment, IS --. Two of the plasmids also carried the gene conferring resistance to florfenicol. The gene was shown to be associated with the insertion sequence IS. Mobile elements appear to contribute to the mobilization of and genes in . The presence of and on the same plasmid highlights the potential risk for a co-selection of the gene through the use of florfenicol in food animal production.

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2010-04-01
2019-11-20
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