1887

Abstract

Most cases of infection in humans are caused by serotype 2 strains, and only a few cases caused by other serotypes have been reported. Among 177 human isolates of in Thailand, 12 (6.8 %) were identified as being of serotype 14, and an occurrence of sporadic serotype 14 infection was noted during 2006–2008, particularly in northern Thailand. Clinical presentations of the 12 patients (median age 62.9 years) included meningitis (58.3 %), septic arthritis (25 %) and sepsis (16.7 %). These clinical features were similar to those previously reported for infections, except that there were no fatal cases. All of the 12 serotype 14 strains belonged to the multilocus sequence types (ST) 105 (=11) and the novel ST127 (=1). Molecular typing by PFGE revealed four different pulsotypes, including an identical pattern for nine ST105 strains and three closely related patterns for two ST105 strains and one ST127 strain. Our PFGE data suggested clonal dissemination of ST105 strains in Thailand. Because serotype 14 is becoming a more common cause of infections in humans, diagnostic tests for serotype 14 should be performed in South-East Asian countries.

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2009-11-01
2019-10-21
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