Detection of bla OXA-58 and bla OXA-23-like genes in carbapenem-susceptible Acinetobacter clinical isolates: should we be concerned?

References

1. Bertini A., Poirel L., Bernabeu S., Fortini D., Villa L., Nordmann P., Carattoli A. 2007; Multicopy bla _OXA-58 gene as a source of high-level resistance to carbapenems in Acinetobacter baumannii . Antimicrob Agents Chemother 51:2324–2328 [CrossRef]
   [Google Scholar]
2. La Scola B., Gundi V. A., Khamis A., Raoult D. 2006; Sequencing of the rpoB gene and flanking spacers for molecular identification of Acinetobacter species. J Clin Microbiol 44:827–832 [CrossRef]
   [Google Scholar]
3. Marti S., Sánchez-Céspedes J., Blasco M. D., Ruiz M., Espinal P., Alba V., Fernández-Cuenca F., Pascual A., Vila J. 2008; Characterization of the carbapenem-hydrolyzing oxacillinase OXA-58 in an Acinetobacter genospecies 3 clinical isolate. Antimicrob Agents Chemother 52:2955–2958 [CrossRef]
   [Google Scholar]
4. Poirel L., Nordmann P. 2006; Genetic structures at the origin of acquisition and expression of the carbapenem-hydrolyzing oxacillinase gene bla _OXA-58 in Acinetobacter baumannii . Antimicrob Agents Chemother 50:1442–1448 [CrossRef]
   [Google Scholar]
5. Poirel L., Marqué S., Héritier C., Segonds C., Charbanon G., Nordmann P. 2005; OXA-58, a novel class D β -lactamase involved in resistance to carbapenems in Acinetobacter baumannii . Antimicrob Agents Chemother 49:202–208 [CrossRef]
   [Google Scholar]
6. Poirel L., Figueiredo S., Cattoir V., Carattoli A., Nordmann P. 2008; Acinetobacter radioresistens as a silent source of carbapenem resistance for Acinetobacter spp. Antimicrob Agents Chemother 52:1252–1256 [CrossRef]
   [Google Scholar]
7. Turton J. F., Ward M. E., Woodford N., Kaufmann M. E., Pike R., Livermore D. M., Pitt T. L. 2006; The role of IS Aba1 in expression of OXA carbapenemase genes in Acinetobacter baumannii . FEMS Microbiol Lett 258:72–77 [CrossRef]
   [Google Scholar]