RT Journal Article SR Electronic(1) A1 Tapsall, John A1 Read, Phillip A1 Carmody, Christopher A1 Bourne, Christopher A1 Ray, Sanghamitra A1 Limnios, Athena A1 Sloots, Theo A1 Whiley, DavidYR 2009 T1 Two cases of failed ceftriaxone treatment in pharyngeal gonorrhoea verified by molecular microbiological methods JF Journal of Medical Microbiology, VO 58 IS 5 SP 683 OP 687 DO https://doi.org/10.1099/jmm.0.007641-0 PB Microbiology Society, SN 1473-5644, AB Diagnostic, genotypic and antibiotic-resistance determinants of Neisseria gonorrhoeae were analysed by molecular methods to verify the failure of ceftriaxone treatment in two cases of pharyngeal gonorrhoea. Monoplex assays were needed to define competitive inhibition of a positive Chlamydia PCR in a duplex assay. Different penA changes were detected in the N. gonorrhoeae isolated from the two cases. These were associated with raised ceftriaxone MICs of 0.03 and 0.016 mg l−1, which may have contributed to the treatment failures in these cases., UL https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.007641-0