1887

Abstract

serogroups displaying the hypermucoviscosity phenotype are associated with a distinct clinical syndrome characterized by liver abscesses, bacteraemia and metastatic lesions. We describe here what we believe to be the first reported case of hypermucoviscous causing a superficial Bartholin's abscess in the absence of systemic involvement.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/jmm.0.006734-0
2009-05-01
2024-12-13
Loading full text...

Full text loading...

/deliver/fulltext/jmm/58/5/671.html?itemId=/content/journal/jmm/10.1099/jmm.0.006734-0&mimeType=html&fmt=ahah

References

  1. Chen Y. J., Kuo H. K., Wu P. C., Kuo M. L., Tsai H. H., Liu C. C., Chen C. H. 2004; A 10-year comparison of endogenous endophthalmitis outcomes: an East Asian experience with Klebsiella pneumoniae infection. Retina 24:383–390 [CrossRef]
    [Google Scholar]
  2. Chuang Y. P., Fang C. T., Lai S. Y., Chang S. C., Wang J. T. 2006; Genetic determinants of capsular serotype K1 of Klebsiella pneumoniae causing primary pyogenic liver abscess. J Infect Dis 193:645–654 [CrossRef]
    [Google Scholar]
  3. Fang C. T., Chuang Y. P., Shun C. T., Chang S. C., Wang J. T. 2004; A novel virulence gene in Klebsiella pneumoniae strains causing primary liver abscess and septic metastatic complications. J Exp Med 199:697–705 [CrossRef]
    [Google Scholar]
  4. Kawai T. 2006; Hypermucoviscosity: an extremely sticky phenotype of Klebsiella pneumoniae associated with emerging destructive tissue abscess syndrome. Clin Infect Dis 42:1359–1361 [CrossRef]
    [Google Scholar]
  5. Ku Y. H., Chuang Y. C., Yu W. L. 2008; Clinical spectrum and molecular characteristics of Klebsiella pneumoniae causing community-acquired extrahepatic abscess. J Microbiol Immunol Infect 41:311–317
    [Google Scholar]
  6. Lee H. C., Chuang Y. C., Yu W. L., Lee N. Y., Chang C. M., Ko N. Y., Wang L. R., Ko W. C. 2006; Clinical implications of hypermucoviscosity phenotype in Klebsiella pneumoniae isolates: association with invasive syndrome in patients with community-acquired bacteraemia. J Intern Med 259:606–614 [CrossRef]
    [Google Scholar]
  7. Liu Y. C., Cheng D. L., Lin C. L. 1986; Klebsiella pneumoniae liver abscess associated with septic endophthalmitis. Arch Intern Med 146:1913–1916 [CrossRef]
    [Google Scholar]
  8. McIver C. J., Janda J. M. 2008; Pathogenesis and laboratory identification of emerging hepatovirulent Klebsiella pneumoniae . Clin Microbiol Newsl 30:127–131 [CrossRef]
    [Google Scholar]
  9. Nadasy K. A., Domiati-Saad R., Tribble M. A. 2007; Invasive Klebsiella pneumoniae syndrome in North America. Clin Infect Dis 45:e25–e28 [CrossRef]
    [Google Scholar]
  10. Nassif X., Fournier J. M., Arondel J., Sansonetti P. J. 1989; Mucoid phenotype of Klebsiella pneumoniae is a plasmid-encoded virulence factor. Infect Immun 57:546–552
    [Google Scholar]
  11. Omole F., Simmons B. J., Hacker Y. 2003; Management of Bartholin's duct cyst and gland abscess. Am Fam Physician 68:135–140
    [Google Scholar]
  12. Struve C., Bojer M., Nielsen E. M., Hansen D. S., Krogfelt K. A. 2005; Investigation of the putative virulence gene magA in a worldwide collection of 495 Klebsiella isolates: magA is restricted to the gene cluster of Klebsiella pneumoniae capsule serotype K1. J Med Microbiol 54:1111–1113 [CrossRef]
    [Google Scholar]
  13. Tanaka K., Mikamo H., Ninomiya M., Tamaya T., Izumi K., Ito K., Yamaoka K., Watanabe K. 2005; Microbiology of Bartholin's gland abscess in Japan. J Clin Microbiol 43:4258–4261 [CrossRef]
    [Google Scholar]
  14. Wang J. H., Liu Y. C., Lee S. S., Yen M. Y., Chen Y. S., Wang J. H., Wann S. R., Lin H. H. 1998; Primary liver abscess due to Klebsiella pneumoniae in Taiwan. Clin Infect Dis 26:1434–1438 [CrossRef]
    [Google Scholar]
  15. Wiskur B. J., Hunt J. J., Callegan M. C. 2008; Hypermucoviscosity as a virulence factor in experimental Klebsiella pneumoniae endophthalmitis. Invest Ophthalmol Vis Sci 49:4931–4938 [CrossRef]
    [Google Scholar]
  16. Yang C. S., Tsai H. Y., Sung C. S., Lin K. H., Lee F. L., Hsu W. M. 2007; Endogenous Klebsiella endophthalmitis associated with pyogenic liver abscess. Ophthalmology 114:876–880 [CrossRef]
    [Google Scholar]
  17. Yeh K. M., Chang F. Y., Fung C. P., Lin J. C., Siu L. K. 2006; magA is not a specific virulence gene for Klebsiella pneumoniae strains causing liver abscess but is part of the capsular polysaccharide gene cluster of K. pneumoniae serotype K1. J Med Microbiol 55:803–804 [CrossRef]
    [Google Scholar]
  18. Yeh K. M., Kurup A., Siu L. K., Koh Y. L., Fung C. P., Lin J. C., Chen T. L., Chang F. Y., Koh T. H. 2007; Capsular serotype K1 or K2, rather than magA and rmpA , is a major virulence determinant for Klebsiella pneumoniae liver abscess in Singapore and Taiwan. J Clin Microbiol 45:466–471 [CrossRef]
    [Google Scholar]
  19. Yu W. L., Ko W. C., Cheng K. C., Lee H. C., Ke D. S., Lee C. C., Fung C. P., Chuang Y. C. 2006; Association between rmpA and magA genes and clinical syndromes caused by Klebsiella pneumoniae in Taiwan. Clin Infect Dis 42:1351–1358 [CrossRef]
    [Google Scholar]
  20. Yu W. L., Ko W. C., Cheng K. C., Lee C. C., Lai C. C., Chuang Y. C. 2008; Comparison of prevalence of virulence factors for Klebsiella pneumoniae liver abscesses between isolates with capsular K1/K2 and non-K1/K2 serotypes. Diagn Microbiol Infect Dis 62:1–6 [CrossRef]
    [Google Scholar]
/content/journal/jmm/10.1099/jmm.0.006734-0
Loading
/content/journal/jmm/10.1099/jmm.0.006734-0
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error