1887

Abstract

infection is endemic in the Mediterranean basin, where it is known as Mediterranean spotted fever, also known as Boutonneuse fever and Marseilles fever. We report the case of a 66-year-old diabetic man who presented a severe form of the disease, complicated by acute renal failure, thrombocytopenia and encephalitis. Diagnosis was confirmed by indirect immunofluorescence assay. Despite appropriate treatment, severe neurological sequelae have remained. Medical literature on encephalitis caused by is also reviewed.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/jmm.0.004465-0
2009-04-01
2019-11-18
Loading full text...

Full text loading...

/deliver/fulltext/jmm/58/4/521.html?itemId=/content/journal/jmm/10.1099/jmm.0.004465-0&mimeType=html&fmt=ahah

References

  1. Amaro, M., Facellar, F. & França, A. ( 2003; ). Report of eight cases of fatal and severe Mediterranean spotted fever in Portugal. Ann N Y Acad Sci 990, 331–343.[CrossRef]
    [Google Scholar]
  2. Bella, F., Font, B., Uriz, S., Muñoz, T., Espejo, E., Traveira, J., Serrano, J. A. & Segura, F. ( 1990; ). Randomized trial of doxycycline versus josamycin for Mediterranean spotted fever. Antimicrob Agents Chemother 34, 937–938.[CrossRef]
    [Google Scholar]
  3. Benhammou, B., Balafrej, A. & Mikou, N. ( 1991; ). Fièvre Boutonneuse méditerranéenne révélée par une atteinte neurologique grave. Arch Fr Pediatr 48, 635–636.
    [Google Scholar]
  4. Brouqui, P., Bacellar, F., Baranton, G., Birtles, R. J., Bjoërsdorff, A., Blanco, J. R., Caruso, G., Cinco, M., Fournier, P. E. & other authors ( 2004; ). Guidelines for the diagnosis of tick-borne bacterial diseases in Europe. Clin Microbiol Infect 10, 1108–1132.[CrossRef]
    [Google Scholar]
  5. Cunha, B. A. ( 2000; ). Minocycline versus doxyxycline in the treatment of Lyme neuroborreliosis. Clin Infect Dis 30, 237–238.
    [Google Scholar]
  6. Ezpeleta, D., Muñoz-Blanco, J. L., Tabernero, C. & Jiménez-Roldán, S. ( 1999; ). Complicaciones neurológicas de la Fiebre Botonosa Mediterránea. Presentación de un caso de encefalomeningomielitis aguda y revisión de la literatura. Neurologia 14, 38–42.
    [Google Scholar]
  7. Font Creus, B., Espejo Arenas, E., Muñoz Espin, R., Uriz Urzainqui, S., Bella Cueto, F. & Segura Porta, F. ( 1991; ). Fiebre Botonosa Mediterránea. Estudio de 246 casos. Med Clin (Barc) 96, 121–125.
    [Google Scholar]
  8. Jensenius, M., Fournier, P. & Raoult, D. ( 2004; ). Rickettsioses and the international traveler. Clin Infect Dis 39, 1493–1499.[CrossRef]
    [Google Scholar]
  9. Marcos Dolado, A., Sánchez Portocarreño, J., Jiménez Madridejo, R., Pontes Navarro, J. C. & García Urra, D. ( 1994; ). Meningoencefalitis por Rickettsia conorii. Aspectos etiopatogénicos, clínicos y diagnósticos. Neurologia 9, 72–75.
    [Google Scholar]
  10. Raoult, D., Weiller, P. J., Chagnon, A., Chaudet, H., Gallais, H. & Casanova, P. ( 1986; ). Mediterranean spotted fever: clinical, laboratory and epidemiological features of 199 cases. Am J Trop Med Hyg 35, 845–850.
    [Google Scholar]
  11. Texier, P., Rousselot, J. M., Quillerou, D., Aufrant, C., Robain, D. & Foucaud, P. ( 1984; ). Fièvre boutonneuse méditerranéenne. A propos d'un cas mortel chez un nouveau-né. Arch Fr Pediatr 41, 51–53.
    [Google Scholar]
  12. Tunkel, A. R., Glaser, C. A., Bloch, K. C., Sejvar, J. J., Marra, C. M., Roos, K. L., Hartman, B. J., Kaplan, S. L., Scheld, W. M. & other authors ( 2008; ). The management of encephalitis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis 47, 303–327.[CrossRef]
    [Google Scholar]
  13. Tzavella, K., Hatzizisis, I. S., Vakalia, A., Mandraveli, K., Zioutas, D. & Alexious-Daniel, S. ( 2006; ). Severe case of Mediterranean spotted fever in Greece with predominant neurological features. J Med Microbiol 55, 341–343.[CrossRef]
    [Google Scholar]
  14. Walker, D. H. & Gear, J. H. S. ( 1985; ). Correlation of the distribution of Rickettsia conorii microscopic lesions, and clinical features in South African tick bite fever. Am J Trop Med Hyg 34, 361–371.
    [Google Scholar]
  15. Walker, D. H. & Raoult, D. ( 2000; ). Rickettsia rickettsi and other spotted fever group rickettsiae (Rocky Mountain spotted fever and other spotted fevers). In Mandell, Douglas, and Bennett's Principles and Practice of Infectious diseases, 5th edn, vol. 2, pp. 2035–2042. Edited by G. L. Mandell, J. E. Bennett & R. Dolin. New York: Churchill Livingstone.
  16. Walker, D. H., Herrero-Herrero, J. I., Ruiz-Beltrán, R., Bullón-Sopellana, A. & Ramos-Hidalgo, A. ( 1987; ). The pathology of fatal Mediterranean spotted fever. Am J Clin Pathol 87, 669–672.
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/jmm.0.004465-0
Loading
/content/journal/jmm/10.1099/jmm.0.004465-0
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error