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, Shea Littlepage1, Del Yazzie2, George Brasinikas3, Loretta Christensen4, Shawnell Damon5, Estar Denny1, Sheri L. Dixon6, Lindsay R. Grant1,†, Marcella Harker-Jones7, James McAuley8
, Pierrette Montanez9, Dennie Parker1, Alisa Reasonover7, Amy Rice10, Kristen Roessler1, Eugene Romancito8, Charis Salabye11, Victoria M. Sergent1, Brenna Simons-Petrusa7, Valerie Tenequer12, Polly Thompson13, Minnie Tsingine14, Robert C. Weatherholtz1 and Laura L. Hammitt1
American Indian (AI) communities in the Southwest have a high burden of invasive pneumococcal disease (IPD) and COVID-19. Through laboratory-based surveillance, the impact of the pandemic on IPD incidence and serotype distribution was evaluated in two AI communities. IPD rates were lower during the pandemic (21.8 vs. 39.0/100 000 pre-pandemic). Rates increased in 2021 compared to 2020 but not to pre-pandemic levels. Cases with SARS-CoV-2 co-infection had a higher case fatality rate (45.2% vs. 17.6% without co-infection). No significant change in serotype distribution was observed. Continued surveillance in these communities is critical to understand the changing IPD burden as the pandemic evolves.
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