1887

Abstract

species are important environmental-related bacteria responsible for diverse infections in humans due to consumption of contaminated water and seafood in underdeveloped areas of the world. This study aimed to investigate the frequency of antimicrobial resistance genes in 577 sequenced and strains isolated in Latin American countries available at the NCBI Pathogen Detection database and to determine the sequence type (ST) of the strains. Almost all strains studied (99.8%) carried at least one antimicrobial resistance gene, while 54.2 % presented a multidrug-resistance profile. The strains exhibited genotypic resistance to 11 antimicrobial classes and , and , which confer resistance to antibiotic peptides, β-lactams and amphenicols, respectively, were the most detected genes. and showed a broad diversity of STs. strains isolated in Haiti after 2010’s earthquake presented the highest diversity and amount of resistance genes in the set of strains analysed and mostly belonged to ST69. In conclusion, the detection of resistance genes from 11 antimicrobial classes and the high number of multidrug-resistant species strains emphasize that Latin American public health authorities should employ more efficient control measures and that special attention should be given for the rational use of antimicrobials in human therapy and aquaculture, since the consumption of contaminated water and seafood with resistant may result in human infections difficult to be treated.

Funding
This study was supported by the:
  • Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Award 001)
    • Principle Award Recipient: FelipePinheiro Vilela
  • Conselho Nacional de Desenvolvimento Científico e Tecnológico (Award 304399/2018-3)
    • Principle Award Recipient: JulianaPfrimer Falcao
  • Fundação de Amparo à Pesquisa do Estado de São Paulo (Award 2019/06947-6)
    • Principle Award Recipient: FelipePinheiro Vilela
  • Fundação de Amparo à Pesquisa do Estado de São Paulo (Award 2019/19338-8)
    • Principle Award Recipient: JulianaPfrimer Falcao
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2021-09-29
2021-10-23
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