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Journal of Medical Microbiology logo Journal of Medical Microbiology

Volume 70, Issue 5

Characterization of -harbouring sequence type 11 international high-risk clones isolated from clinical samples in Yangon General Hospital, a tertiary-care hospital in Myanmar No Access

Abstract

Fifteen isolates harbouring genes were identified from blood and sputum specimens of patients at a tertiary-care facility (Yangon General Hospital, Yangon, Myanmar) in 2018. Two of the isolates belonged to sequence type (ST) 11, an international high-risk clone. Whole-genome sequencing and phylogenetic analyses revealed that these two isolates were clustered together with other ST11 isolates originating from other countries. The isolates harboured the gene on an IncFII-type plasmid that is prevalent among carbapenemase-producing in Yangon but has rarely been found in other ST11 isolates. Our data suggests the regional presence of the ST11 international high-risk clone and its acquisition of an endemic -carrying plasmid.

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Keyword(s): blaNDM-5 , carbapenem-resistant Enterobacteriaceae , IncFII , Klebsiella pneumoniae and Myanmar
Funding
This study was supported by the:
  • Japan Agency for Medical Research and Development
    • Principal Award Recipient: ShigeyukiHamada
© 2021 The Authors
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/content/journal/jmm/10.1099/jmm.0.001348
2021-05-26
2025-12-09

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/content/journal/jmm/10.1099/jmm.0.001348
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Characterization of blaNDM-5-harbouring Klebsiella pneumoniae sequence type 11 international high-risk clones isolated from clinical samples in Yangon General Hospital, a tertiary-care hospital in Myanmar
J. Med. Microbiol. 70, 001348 (2021); https://doi.org/10.1099/jmm.0.001348
/content/journal/jmm/10.1099/jmm.0.001348
/content/journal/jmm/10.1099/jmm.0.001348
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