1887

Abstract

This study tests the release of SARS-CoV-2 RNA into the air during normal breathing, without any sign of possible risk of contagion such as coughing, sneezing or talking. Five patients underwent oropharyngeal, nasopharyngeal and salivary swabs for real-time reverse transcriptase PCR (RT-PCR) detection of SARS-CoV-2 RNA. Direct SARS-CoV-2 release during normal breathing was also investigated by RT-PCR in air samples collected using a microbiological sampler. Viral RNA was detected in air at 1 cm from the mouth of patients whose oropharyngeal, nasopharyngeal and salivary swabs tested positive for SARS-CoV-2 RNA. In contrast, the viral RNA was not identified in the exhaled air from patients with oropharyngeal, nasopharyngeal and salivary swabs that tested negative. Contagion of SARS-CoV-2 is possible by being very close to the mouth of someone who is infected, asymptomatic and simply breathing.

Funding
This study was supported by the:
  • Other (Award This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors, however was partially support with research funds (ex60%) of DISPUTER.)
    • Principle Award Recipient: PIERODI CARLO
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. The Microbiology Society waived the open access fees for this article.
Loading

Article metrics loading...

/content/journal/jmm/10.1099/jmm.0.001328
2021-02-25
2021-10-28
Loading full text...

Full text loading...

/deliver/fulltext/jmm/70/3/jmm001328.html?itemId=/content/journal/jmm/10.1099/jmm.0.001328&mimeType=html&fmt=ahah

References

  1. SWX O, Tan YK, Chia PY, Lee TH, OT N. Air, surface environmental, and personal protective equipment contamination by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from a symptomatic patient. JAMA 2020; 323:16
    [Google Scholar]
  2. Guan W, Ni Z, Hu Y, Liang W, Ou C et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 2020; 382:1708–1720 [View Article][PubMed]
    [Google Scholar]
  3. Lewis D. Is the coronavirus airborne? Experts can't agree. Nature 2020; 580:175 [View Article][PubMed]
    [Google Scholar]
  4. Xu R, Cui B, Duan X, Zhang P, Zhou X et al. Saliva: potential diagnostic value and transmission of 2019-nCoV. Int J Oral Sci 2020; 12:1 [View Article]
    [Google Scholar]
  5. Barone M, Ucciferri C, Cipollone G, Mucilli F. Recombinant human angiotensin-converting enzyme 2 and COVID-19 acute respiratory distress syndrome: a theoretical or a real resource?. EJMO 2020; 4:139–140
    [Google Scholar]
  6. Ucciferri C, Auricchio A, Di Nicola M, Potere N, Abbate A, Cipollone F et al. Canakinumab in a subgroup of patients with COVID-19. Lancet Rheumatol 2020; 2:e457–ee458 [View Article][PubMed]
    [Google Scholar]
  7. Ucciferri C, Barone M, Vecchiet J, Falasca K. Pidotimod in Paucisymptomatic SARS-CoV2 infected patients. Mediterr J Hematol Infect Dis 2020; 12:e2020048 [View Article][PubMed]
    [Google Scholar]
  8. Feng S, Shen C, Xia N, Song W, Fan M et al. Rational use of face masks in the COVID-19 pandemic. The Lancet Resp Med 2020; 8:434–436 [View Article]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/jmm.0.001328
Loading
/content/journal/jmm/10.1099/jmm.0.001328
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error