@article{mbs:/content/journal/jmm/10.1099/jmm.0.000817, author = "Takeuchi, Dan and Akeda, Yukihiro and Yoshida, Hisao and Hagiya, Hideharu and Yamamoto, Norihisa and Nishi, Isao and Yoshioka, Nori and Sugawara, Yo and Sakamoto, Noriko and Shanmugakani, Rathina Kumar and Deguchi, Matsuo and Tomono, Kazunori and Hamada, Shigeyuki", title = "Genomic reorganization by IS26 in a blaNDM-5-bearing FII plasmid of Klebsiella pneumoniae isolated from a patient in Japan", journal= "Journal of Medical Microbiology", year = "2018", volume = "67", number = "9", pages = "1221-1224", doi = "https://doi.org/10.1099/jmm.0.000817", url = "https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.000817", publisher = "Microbiology Society", issn = "1473-5644", type = "Journal Article", keywords = "blaNDM-5", keywords = "IS26", keywords = "IncFII plasmid", keywords = "genomic reorganization", abstract = "An NDM-5-producing Klebsiella pneumoniae ST147 strain was isolated from a Japanese patient who had not travelled abroad in at least 5 years. Whole-genome sequencing revealed a genomic rearrangement in an FII plasmid harbouring bla NDM-5 due to the replicative transposition of IS26. A hypothetical structure was proposed for its ancestral plasmid, and comparative genomic analysis of the plasmid suggested the dissemination of structurally similar plasmids harbouring bla NDM-5 in Asian and Middle Eastern countries.", }