1887

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Volume 67, Issue 7

Occurrence and characterization of extended-spectrum cephalosporin-resistant in healthy household dogs in Greece Free

Abstract

Extended-spectrum cephalosporin- and/or carbapenem-resistant (ESC and/or Carb) constitute a public health hazard because of limited treatment options and are endemic among humans in Greece. Recently, ESC and Carb have been increasingly isolated from companion animals, stressing their potential role as a reservoir for humans. However, the presence of ESC bacteria in companion animals within Greek households has not been determined yet. Genes conferring the ESC and Carb phenotype were detected among canine isolates and their chromosomal or plasmid location was determined. Standard methods were applied for plasmid characterization. The clonal relatedness of the recovered isolates was examined by multilocus sequence typing (MLST). Here, we report the first findings on the presence of ESC in healthy Greek dogs. ESC isolates were associated with different sequence types (STs), including the human pandemic ST131 clone. The occurrence of human-related ESBL/pAmpC genes, plasmid types and/or strain STS in this animal reservoir suggests possible bilateral transmission.

  • Received:
  • Accepted:
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Keyword(s): companion animals , E. coli , ESBL , K. pneumoniae , MLST and plasmid
© 2018 The Authors
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2018-07-01
2024-04-24
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Occurrence and characterization of extended-spectrum cephalosporin-resistant Enterobacteriaceae in healthy household dogs in Greece
J. Med. Microbiol. 67, 931 (2018); https://doi.org/10.1099/jmm.0.000768
/content/journal/jmm/10.1099/jmm.0.000768
/content/journal/jmm/10.1099/jmm.0.000768
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