Brucellosis is a challenging zoonosis to diagnose and treat. The recent outbreaks of RB51 in several states in the United States, including New Jersey and Texas, due to raw milk consumption has raised the concern of drug-resistant spp. This commentary highlights the importance of being on the lookout for this emerging infection.


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  1. Centers for Disease Control and Prevention (CDC) 2012; Brucellosis Reference Guide: Exposures, Testing, and Prevention. www.cdc.gov/brucellosis/pdf/brucellosi-reference-guide.pdf [Accessed on December 10, 2017]
  2. Centers for Disease Control and Prevention (CDC) Brucella suis infection associated with feral swine hunting – three states, 2007-2008. MMWR Morb Mortal Wkly Rep 2009; 58:618–621[PubMed]
    [Google Scholar]
  3. Centers for Disease Control and Prevention (CDC) Update: potential exposures to attenuated vaccine strain Brucella abortus RB51 during a laboratory proficiency test—United States and Canada, 2007. MMWR Morb Mortal Wkly Rep 2008; 57:36–39[PubMed]
    [Google Scholar]
  4. Food and Drug Administration (FDA) FDA Alerts Consumers about Risk of Antibiotic-Resistant Brucella Linked to Raw Milk from Udder Milk Co-Op. U.S; 2017 www.fda.gov/Food/RecallsOutbreaksEmergencies/Outbreaks/ucm585655.htm [Accessed on December 11, 2017]
  5. Centers for Disease Control and Prevention (CDC) 2017; CDC and Texas Health Officials Warn About Illness Linked to Raw Milk from Texas Dairy. www.cdc.gov/brucellosis/clinicians/rb51-raw-milk.html [Accessed on December 10, 2017]
  6. Voelker R. Brucella in Raw Milk Prompts Health Warning in Texas. JAMA 2017; 318:1533 [View Article][PubMed]
    [Google Scholar]
  7. Ferreira L, Vega Castaño S, Sánchez-Juanes F, González-Cabrero S, Menegotto F et al. Identification of Brucella by MALDI-TOF mass spectrometry. Fast and reliable identification from agar plates and blood cultures. PLoS One 2010; 5:e14235 [View Article][PubMed]
    [Google Scholar]
  8. Vrioni G, Gartzonika C, Kostoula A, Boboyianni C, Papadopoulou C et al. Application of a polymerase chain reaction enzyme immunoassay in peripheral whole blood and serum specimens for diagnosis of acute human brucellosis. Eur J Clin Microbiol Infect Dis 2004; 23:194–199 [View Article][PubMed]
    [Google Scholar]
  9. Zerva L, Bourantas K, Mitka S, Kansouzidou A, Legakis NJ et al. Serum is the preferred clinical specimen for diagnosis of human brucellosis by PCR. J Clin Microbiol 2001; 39:1661–1664 [View Article][PubMed]
    [Google Scholar]
  10. Lusk Pfefer TS, Timme R, Kase JA. Identification of Brucella genus and eight Brucella species by Luminex bead-based suspension array. Food Microbiol 2018; 70:113–119 [View Article][PubMed]
    [Google Scholar]
  11. Winchell JM, Wolff BJ, Tiller R, Bowen MD, Hoffmaster AR. Rapid identification and discrimination of Brucella isolates by use of real-time PCR and high-resolution melt analysis. J Clin Microbiol 2010; 48:697–702 [View Article][PubMed]
    [Google Scholar]
  12. Baum M, Zamir O, Bergman-Rios R, Katz E, Beider Z et al. Comparative evaluation of microagglutination test and serum agglutination test as supplementary diagnostic methods for brucellosis. J Clin Microbiol 1995; 33:2166–2170[PubMed]
    [Google Scholar]
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