%0 Journal Article %A Dafopoulou, K. %A Tsakris, A. %A Pournaras, S. %T Changes in antimicrobial resistance of clinical isolates of Acinetobacter baumannii group isolated in Greece, 2010–2015 %D 2018 %J Journal of Medical Microbiology, %V 67 %N 4 %P 496-498 %@ 1473-5644 %R https://doi.org/10.1099/jmm.0.000708 %K trimethoprim/sulfamethoxazole %K carbapenems %K resistance rates %K cumulative susceptibilities %K antimicrobials %I Microbiology Society, %X In recent years, hospitals in southeastern Europe have faced dramatically high rates of antibiotic-resistant Acinetobacter baumannii. We analysed the evolution of resistance among clinical isolates of A. baumannii group obtained from nine tertiary hospitals throughout Greece over 6 years (2010–2015). Identification and antimicrobial susceptibility testing were performed using Vitek 2 or Microscan walkaway automated systems. Between 2010 and 2015, resistance to ampicillin/sulbactam increased from 46.2 to 88.2 % (P=0.021), resistance to gentamicin increased from 69.3 to 86.4 % (P=0.014) and resistance to tobramycin increased from 59.8 to 76.8 % (P=0.011). Imipenem resistance rates were consistently very high, ranging from 90.3 % in 2010 to 94.5 % in 2015 (P=0.198), while meropenem resistance rates increased from 82.6 % in 2010 to 94.8 % in 2015 (P=0.006). Resistance rates to trimethoprim/sulfamethoxazole showed a remarkable decreasing trend, declining from 90.2 % in 2010 to 69.1 % in 2015 (P=0.035). These evolutions render the treatment of A. baumannii infections particularly challenging and underline the need for enhanced infection control measures. %U https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.000708