1887

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Volume 66, Issue 12

Antimicrobial susceptibility, virulence potential and sequence types associated with strains recovered from human faeces Free

Abstract

The genus includes bacteria that are considered emergent pathogens because they can produce infections in humans and animals. The most common symptoms are bloody and non-bloody persistent diarrhea but cases with abdominal cramps without diarrhea or asymptomatic cases have also been described as well as cases with bacteremia. The objective was to characterize clinical strains isolated from the faeces of patients from three Spanish hospitals.

We have characterized 28 clinical strains (27 of and one of ) isolated from faeces, analysing their epidemiological relationship using the multilocus sequence typing (MLST) approach and screening them for their antibiotic susceptibility and for the presence of virulence genes.

Typing results showed that only one of the 28 identified sequence types (i.e. ST 2) was already present in the MLST database. The other 27 STs constituted new records because they included new alleles for five of the seven genes or new combinations of known alleles of the seven genes. All strains were positive for the virulence gene and sensitive to tetracycline. However, 7.4 % of the and strains showed resistance to ciprofloxacin.

The fact that epidemiological unrelated strains show the same ST indicates that other techniques with higher resolution should be developed to effectively recognize the infection source. Resistance to ciprofloxacin, one of the antibiotics recommended for the treatment of intestinal infections, demonstrated in 10.7 % of the strains, indicates the importance of selecting the most appropriate effective treatment.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): antibiotic resistance , Arcobacter butzleri , Arcobacter cryaerophilus , MLST and virulence genes
© 2017 The Authors
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2017-12-01
2024-04-19
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Antimicrobial susceptibility, virulence potential and sequence types associated with Arcobacter strains recovered from human faeces
J. Med. Microbiol. 66, 1736 (2017); https://doi.org/10.1099/jmm.0.000638
/content/journal/jmm/10.1099/jmm.0.000638
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