Prevalence and genetic diversity of in the general population of Granada and co-infections with and species Free

Abstract

Purulent or exudative genitourinary infections are a frequent cause of consultation in primary and specialized healthcare. The objectives of this study were: to determine the prevalence of and co-infections with and in vaginal secretion; and to use multilocus sequence typing (MLST) to analyse the genetic diversity of strains.

The samples were submitted for analysis (=5230) to a third-level hospital in Granada (Southern Spain) between 2011 and 2014; eight strains isolated during 2015 were randomly selected for MLST analysis. Culture and nucleic acid hybridization techniques were used to detect microorganisms in the samples.

The prevalence of was 2.4 % between 2011 and 2014, being higher during the first few months of both 2011 and 2012. Among samples positive for , co-infection with was detected in 29 samples and co-infection with spp. in 6, while co-infection with all three pathogens was observed in 3 samples. The only statistically significant between-year difference in co-infection rates was observed for with due to an elevated rate in 2011. MLST analysis results demonstrated a high genetic variability among strains circulating in our setting.

These findings emphasize the need for the routine application of diagnostic procedures to avoid the spread of this sexually transmitted infection.

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2017-10-01
2024-03-28
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