1887

Abstract

Dissemination of resistance to carbapenems among through plasmids is an increasingly important concern in health care worldwide. Here we report the first description of an IncX3 plasmid carrying the gene in a strain of isolated from a kidney-liver transplanted patient at the transplantation centre ISMETT (Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, Palermo, Italy). To localize the transposable element containing the resistance-associated gene Next-Generation Sequencing of the bacterial DNA was performed. was positive for and genes. The molecular analysis demonstrated that the gene of this bacterial strain was located in one copy of the Tn-3-like element Tn carried in a plasmid that is 53 392 bp in size and showed the typical IncX3 scaffold. Our data demonstrated the presence of a new harbouring the IncX3 plasmid in . The possible dissemination among of this type of plasmid should be monitored and evaluated in terms of clinical risk.

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2017-10-01
2024-12-06
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