1887

Journal of Medical Microbiology logo

Volume 66, Issue 6

Evaluation of self-collected rectal swabs for the detection of bacteria responsible for sexually transmitted infections in a cohort of HIV-1-infected patients Free

The Microbiology Society has been notified that this paper is being reviewed as part of a “scientific misconduct investigation” by the University of Aix-Marseille and the French authorities. This Editor’s Note is issued until the findings of that investigation are published, and any further action will be agreed with the Microbiology Society’s Publishing Panel. 

Abstract

The standard approach to screening sexually transmitted infections (STIs) has often been restricted to urogenital specimens. Most current guidelines, however, also recommend testing extra-genital sites, including rectal locations, because asymptomatic rectal carriage of pathogens has often been reported. The aim of our study was to evaluate self-collected rectal swabs to screen bacterial STIs in HIV-infected patients in Marseille, France.

Between January 2014 and December 2015, 118 HIV-infected patients (93 males and 25 females) agreed to self-sample anal swabs for detection of bacterial STI. Detection of , , , and was performed using in-house qPCR assay.

Bacterial STIs were found in 8 % (9/118) of the patients. was the most commonly detected bacterium (4.2 %) followed by (2.5 %), (1.7 %) and (0.8 %). All the positive patients were males. The rectal carriage of pathogenic bacteria was fortuitously discovered for seven men (78 %) who did not present rectal signs of STIs and was suspected for two men who presented proctitis (22 %).

In conclusion, testing extra-genital sites is crucial for the diagnosis of STIs in men and women presenting or not concomitant urogenital infections in order to detect asymptomatic carriage with the aim of controlling and preventing transmission to their sexual partners.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): anorectal , Chlamydia trachomatis , HIV , Mycoplasma genitalium , Neisseria gonorrhoeae , qPCR , screening , STI and Treponema pallidum
© 2017 The Authors
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2017-06-01
2024-04-20
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Evaluation of self-collected rectal swabs for the detection of bacteria responsible for sexually transmitted infections in a cohort of HIV-1-infected patients
J. Med. Microbiol. 66, 693 (2017); https://doi.org/10.1099/jmm.0.000481
/content/journal/jmm/10.1099/jmm.0.000481
/content/journal/jmm/10.1099/jmm.0.000481
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