1887

Abstract

We studied ceftaroline combinations against 61 meticillin-resistant isolates; 18 of them were also resistant to linezolid, using overlapping E-test method. Daptomycin–ceftaroline combination obtained lower fractional inhibitory concentration values, in comparison with those including vancomycin or linezolid against meticillin-resistant (<0.05). All meticillin- and linezolid-resistant strains were resistant to ceftaroline; nevertheless, combinations with vancomycin or daptomycin showed higher synergy or addition rates than those with linezolid.

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2016-10-18
2020-12-02
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