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Volume 65, Issue 1

Challenges facing the drug discovery pipeline for non-tuberculous mycobacteria Free

Abstract

Non-tuberculous mycobacteria (NTM) infections are increasingly being reported worldwide. They are a major concern for healthcare professionals for multiple reasons, ranging from the intrinsic resistance of NTM to most conventionally utilized antimicrobials to inharmonious diagnostic criteria utilized for evaluation of NTM-infected patients, leading to high morbidity. In this review, we highlight the paucity of drugs having potent anti-NTM activity amongst the new antimicrobials currently under various stages of development for anti-tubercular activity and issue a call for the establishment of a concerted dedicated drug discovery pipeline targeting NTM.

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© 2016 The Authors
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2016-01-01
2024-04-18
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Challenges facing the drug discovery pipeline for non-tuberculous mycobacteria
J. Med. Microbiol. 65, 1 (2016); https://doi.org/10.1099/jmm.0.000198
/content/journal/jmm/10.1099/jmm.0.000198
/content/journal/jmm/10.1099/jmm.0.000198
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