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Volume 64, Issue 7

Genetic tools for manipulating genome: an overview Free

Abstract

is an emerging nosocomial pathogen involved in a variety of infections ranging from minor soft-tissue infections to more severe infections such as ventilator-associated pneumonia and bacteraemia. has become resistant to most of the commonly used antibiotics and multidrug-resistant isolates are becoming a severe problem in the healthcare setting. In the past few years, whole-genome sequences of >200 isolates have been generated. Several methods and molecular tools have been used for genetic manipulation of various spp. Here, we review recent developments of various genetic tools used for modification of the genome, including various ways to inactivate gene function, chromosomal integration and transposon mutagenesis

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2015-07-01
2024-09-18
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Genetic tools for manipulating Acinetobacter baumannii genome: an overview
J. Med. Microbiol. 64, 657 (2015); https://doi.org/10.1099/jmm.0.000081
/content/journal/jmm/10.1099/jmm.0.000081
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